...Sai Sravani Vennam; Valentina Talevi; Geethika Venkataraman; Rayyan Ahmed Syed; Xinruo Zhang; Baba B. Mass; Venkata Saroja Voruganti Introduction: Excess fructose intake has been linked to increased risk of dyslipidemia, insulin resistance, hyperuricemia, inflammation, and obesity. In this human...

..., weight loss interventions, nutrients and nutritional bioactive compounds can modulate the expression of various microRNA (miRNAs) and DNA methylation levels, contributing to the development of metabolic disorders such as obesity and type 2 diabetes. Furthermore, several studies have proposed that DNA...

... of this study was to evaluate the role of rs822393 of ADIPOQ gene on adiponectin levels and metabolic parameters after weight loss with a high-fat hypocaloric diet with Mediterranean pattern during 12 weeks. Methods: A population of 283 patients with obesity was allocated to a dietary intervention trial...

...Omar Ramos-Lopez; Yesenia Martinez-Aceviz; Ana Alondra Sobrevilla-Navarro; Jose Roman Chavez-Mendez Introduction: It has been suggested that capsaicin (CAP), a major pungent component in chili peppers, can be used as an anti-obesity ingredient due to effects on energy metabolism, but evidence...

... studies have contributed to characterize specific bacteria associated with obesity. This review covers the information driven by gut bacterial profiling analyses and emphasizes the potential application of this knowledge in precision nutrition strategies for obesity understanding and weight loss...

...) substantially alters the gut microbial composition which could be associated with the metabolic improvements seen after surgery. Few studies have been conducted in Latin American populations, such as Mexico, where obesity prevalence is above 30% in the adult population. Thus, the aim of this study...

...Adolfo G. Cuevas; Frank D. Mann; Robert F. Krueger Introduction: Exposure to discrimination has emerged as a risk factor for obesity. It remains unclear, however, whether the genotype of the individual can modulate the sensitivity or response to discrimination exposure (gene × environment...

...Mariana Perez-Robles; Wendy Campos-Perez; Joel Torres-Vanegas; Sarai Citlalic Rodriguez-Reyes; Juan José Rivera-Valdés; Erika Martínez-Lopez Introduction: Obesity is a prevalent multifactorial disease whose main complication is dyslipidemia. Serum lipid levels also depend on genetic factors...

...Louis Pérusse; Raphaëlle Jacob; Vicky Drapeau; Clare Llewellyn; Benoit J. Arsenault; Alexandre Bureau; Marie-Ève Labonté; Angelo Tremblay; Marie-Claude Vohl Background: Obesity results from complex interactions between genetic susceptibility to weight gain and poor eating and lifestyle behaviors...

... that triggers a strong release of cytokines, which then modulates the immune system and results in hyperinflammation. Today’s diet is high in omega-6 fatty acids and deficient in omega-3 fatty acids; this, along with a high fructose intake, leads to obesity, which is a chronic state of low-grade inflammation...

...Won-Jun Lee; Ji Eun Lim; Hae Un Jung; Ji-One Kang; Taesung Park; Sungho Won; Sang Youl Rhee; Mi Kyung Kim; Yeon-Jung Kim; Bermseok Oh Introduction: Obesity results from an imbalance in the intake and expenditure of calories that leads to lifestyle-related diseases. Although genome-wide association...

.... Metabolically unhealthy phenotype Adiponectin Obesity Genetic variants Research Article Lifestyle Genomics 2020;13:172 179 DOI: 10.1159/000510021 Received: May 2, 2020 Accepted: July 8, 2020 Published online: November 2, 2020 A Metabolically Unhealthy Phenotype Is Associated with ADIPOQ Genetic Variants...

... of results following clinical trials investigating the effects of saturated (SFA) and unsaturated fat intake. This variability may be due to genetic differences. Individuals with obesity are at an increased risk for adverse cardiometabolic health and dyslipidemia, and often present with the combined...

..., instructions or products referred to in the content or advertisements. 2020 Physical activity Lifestyle genomics Obesity Randomized clinical trial Genetics Regular physical activity (PA) is associated with numerous health benefits, including reduced stress and increased energy levels...

...Pui Yee Tan; Soma Roy Mitra Background: Computing polygenic risk scores (PRS) to predict the degree of risk for obesity may contribute to weight management programs strategically. Objectives: To investigate the combined effect of FTO rs9930501, rs9930506, and rs9932754 and ADRB2 rs1042713...

...Catherine A.M. Graham; Charles R. Pedlar; Gary Hearne; Silvia Lorente-Cebrián; Pedro González-Muniesa; Yiannis Mavrommatis Introduction: In the UK, the number of comorbidities seen in children has increased along with the worsening obesity rate. These comorbidities worsen into adulthood. Genome...

... amounts of dietary fat in two hypocaloric diets. Design: A population of 283 obese patients was recruited in a randomized clinical trial with two diets: Diet HF (high-fat diet: 38% carbohydrates, 24% proteins, and 38% fats) versus Diet LF (low-fat diet: 53% carbohydrates, 20% proteins, and 27% fats...