Die hochauflösende Computertomografie (high-resolution computed tomography; HRCT) ist ein wichtiges diagnostisches Instrument in der Pneumologie. Das «Blütenbaum»-Zeichen ist ein häufiger Befund in HRCT-Scans. Zu den häufigsten Differenzialdiagnosen beim «Blütenbaum»-Zeichen zählen Infektionen mit Mycobacterium tuberculosis, nichttuberkulösen Mykobakterien und anderen pathogenen Bakterien, Pilzen oder Viren. Weitere mögliche Gründe sind immunologische, kongenitale und idiopathische Erkrankungen sowie die Aspiration oder Inhalation von toxischen Substanzen. Maligne Erkrankungen sind selten vorkommende Differenzialdiagnosen. Wir stellen einen Fall mit «Blütenbaum»-förmiger pulmonaler Infiltration einer chronischen lymphatischen Leukämie vor, die nur durch transbronchiale Biopsien diagnostiziert werden konnte, und gehen auf andere Differenzialdiagnosen ein.

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