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Keywords: Efficacy
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Journal Articles
Subject Area:
Dermatology
Kompass Dermatol (2024) 12 (2): 88–89.
Published Online: 08 April 2024
...Irena Neustädter; Sophie Blatt Background: For children aged 6-11 years with uncontrolled severe atopic dermatitis (AD), 16 weeks of treatment with dupilumab resulted in substantial clinical benefit compared with placebo with an acceptable safety profile. However, longer-term safety and efficacy...
Journal Articles
Kompass Dermatol (2023) 11 (2): 76–77.
Published Online: 20 April 2023
...Felix Lauffer Background: Effective, well-tolerated oral psoriasis treatments are needed. Objective: To compare the efficacy and safety of deucravacitinib, an oral, selective, allosteric tyrosine kinase 2 inhibitor, versus placebo and apremilast in adults with moderate to severe plaque psoriasis...
Journal Articles
Kompass Dermatol (2022) 10 (4): 184–185.
Published Online: 07 November 2022
... pemphigus by suppressing B-cell signaling. Objective: We investigated the efficacy and safety of tirabrutinib in patients with refractory pemphigus. Methods: This was a multicenter, open-label, single-arm phase 2 study of Japanese patients with refractory pemphigus receiving appropriate treatment...
Journal Articles
Subject Area:
Dermatology
Kompass Dermatol (2022) 10 (1): 12–13.
Published Online: 28 January 2022
... with <10% CD30 expression), or CD30min ≥ 10% (all biopsies with ≥10% CD30 expression) and baseline LCT present or absent. Efficacy analyses were the proportion of patients with objective response lasting ≥4 months (ORR4) and progression-free survival (PFS). Results: Clinical activity with brentuximab...
Journal Articles
Subject Area:
Dermatology
Kompass Dermatol (2019) 7 (1): 20–21.
Published Online: 26 February 2019
..., there is a high demand for dermocosmetics that do not provoke such reactions and are suitable for use in rosacea. The present guideline of the Society for Dermopharmacy describes the requirements that dermocosmetics for use in rosacea should meet. They include, inter alia, methods to prove the efficacy...