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Keywords: Podocyte
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Journal Articles
Journal Articles
Subject Area:
Nephrology
Kidney Dis (2022) 8 (4): 308–318.
Published Online: 30 May 2022
... major advances, since the discovery of the phospholipase A2 receptor as the major autoantigen of podocytes in MN, the mechanisms leading to glomerular damage remain elusive. Pyroptosis, a newly discovered type of programed necrotic cell death mainly mediated by gasdermin, was found to be responsible...
Journal Articles
Subject Area:
Nephrology
Kidney Dis (2021) 7 (6): 438–451.
Published Online: 01 September 2021
...Yu Sun; Sijia Cui; Yunfeng Hou; Fan Yi Background: Podocytes, functionally specialized and terminally differentiated glomerular visceral epithelial cells, are critical for maintaining the structure and function of the glomerular filtration barrier. Podocyte injury is considered as the most...
Journal Articles
Subject Area:
Nephrology
Kidney Dis (2021) 7 (4): 254–267.
Published Online: 25 May 2021
..., instructions or products referred to in the content or advertisements. Autophagy Lysosome Kidney disease Tubular epithelial cell Podocyte Macroautophagy is an evolutionarily conserved lysosome-dependent catabolic process that sequesters the cytoplasmic materials, such as protein aggregates...
Journal Articles
Subject Area:
Nephrology
Kidney Dis (2020) 6 (6): 422–433.
Published Online: 23 October 2020
... as a renal disease indicator is dampened by the difficulty to ascertain their cell source. Objectives: The aim of this study was to demonstrate that podocytes can release migrasomes, a unique class of microvesicle with size ranging between 400 and 2,000 nm, and the urine level of migrasomes may serve...
Journal Articles
Subject Area:
Nephrology
Kidney Dis (2020) 6 (5): 324–329.
Published Online: 27 May 2020
... kidney function. Diabetes, hypertension, and any primary or secondary glomerulopathy may threaten the normal glomerular function. In fact, any glomerular insult may alter the glomerular filtration barrier, which in turn is composed by the podocyte, the glomerular basement membrane, and the capillary...
Journal Articles
Subject Area:
Nephrology
Kidney Dis (2018) 4 (2): 83–94.
Published Online: 22 May 2018
...Min Zhao; Mi Bai; Guixia Ding; Yue Zhang; Songming Huang; Zhanjun Jia; Aihua Zhang Background: We previously reported that the NLRP3 inflammasome played an important role in mediating the podocyte injury induced by aldosterone. However, more studies on the role of the NLRP3 inflammasome...
Journal Articles
Subject Area:
Nephrology
Kidney Dis (2017) 3 (2): 50–56.
Published Online: 31 May 2017
... in hereditary podocytopathies. Moreover, it has revealed mutations in unexpected genes and has widened the phenotypes associated with podocyte gene mutations. The list of genes mutated in hereditary podocytopathies is constantly evolving and consists to date of more than 40 genes. However, the most recently...