... kidney disease Sodium-glucose cotransporter-2 inhibitors Clinical trials Mortality Outcomes Chronic kidney disease (CKD) is the 16th leading cause of mortality worldwide, with an estimated global prevalence of 11–13% [ 1, 2 ]. The incidence of CKD and its contribution to mortality and other...

...Wayne L. Miller; Diane E. Grill; Qi Qian Background: Cardiorenal interconnections are complex and may in part be mediated by the extent of intravascular volume expansion. The impact of subclinical volume excess on outcomes in heart failure (HF) patients with chronic kidney disease (CKD) has...

... approaches) of CRS in Western countries (Europe and United States). Cardiorenal syndrome Western countries Risk factors Diagnosis Outcomes Treatment The term cardiorenal syndrome (CRS) has been used to define different clinical conditions in which heart dysfunction and kidney dysfunction...

...Josée Bouchard; Ravindra L. Mehta Background: Acute kidney injury (AKI) is frequent and is associated with poor outcomes, including increased mortality, higher risk of chronic kidney disease, and prolonged hospital lengths of stay. The epidemiology of AKI mainly derives from studies performed...