... remains unclear. Here, we investigated the causal relationship between gut microbiota and different kidney diseases through mendelian randomization analysis. Methods: Gut microbiota and three types of kidney diseases, including diabetic nephropathy, IgA nephropathy, and membranous nephropathy, were...

..., such as diabetic nephropathy, kidney injury, IgA nephropathy, chronic kidney diseases, clear cell renal cell carcinoma, end-stage renal disease, canine leishmaniosis-induced kidney disease, kidney fibrosis, and aristolochic acid nephropathy. Mechanistically, the role of LRG1 in kidney diseases is believed...

...Shuang Xu; Xinyuan Li; Qing Hou; Ning Xu; Qingmiao Lu; Sudan Wang; Chunsun Dai Introduction: Unsaturated fatty acids play an essential role in the progression of diabetic nephropathy (DN). However, previous studies were mainly focused on the role of individual unsaturated fatty acid. The serum...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2022 C-reactive protein CD32 Acute kidney injury UUO Diabetic nephropathy C-reactive protein (CRP), a pentameric protein consisting...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2022 Long noncoding RNA maternally expressed gene 3 Diabetic nephropathy Inflammation Fibrosis Myeloid differentiation primary-response protein 88 Diabetic nephropathy (DN...

...Ting Zhou; Yiyun Wang; Li Shen; Xiaomei Li; Qiong Jiao; Ze Li; Junjie Jia; Li He; Qunzi Zhang; Niansong Wang; Ying Fan Introduction: Clinical indicators or pathological features alone cannot reliably predict renal survival in patients with biopsy-confirmed diabetic nephropathy (DN). Therefore...

... on the prevalence of diabetic nephropathy (DN) and coexistence of non-diabetic renal disease (NDRD) in a cohort of 255 non-insulin-dependent diabetes mellitus (NIDDM) patients aims to determine the value of performing renal biopsies in these patients and elucidate the factors which could affect their progression...

... the progression of chronic kidney disease (CKD), and the objective of this review is to discuss the pathophysiology, and role of ET and endothelin receptor antagonists (ERAs) in CKD. Summary: The use of ERAs in hypertensive nephropathy has the potential to decrease proteinuria, and in diabetic nephropathy has...

... nephritis Diabetic nephropathy Renal biopsy Glomerular disease still remains a leading cause of end-stage renal failure worldwide. We undertake this review because we believe that an understanding of the changing pattern of glomerulonephritis (GN) worldwide will enable us to use...

... levels in patients with 3 common types of secondary FSGS: Alport’s syndrome (Alport-FSGS), obesity-related FSGS, and diabetic nephropathy. Methods: Fifty-two secondary FSGS patients diagnosed by kidney biopsy, including 8 with Alport-FSGS, 20 with obesity-related FSGS, and 24 with diabetic nephropathy...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Nephro Update Europe Diabetic nephropathy Peritoneal dialysis Glomerulonephritis Hepatitis C update Hypertension update The annual Nephro Update Europe took...

...Ling Wei; Ying Xiao; Li Li; Xiaofen Xiong; Yachun Han; Xuejing Zhu; Lin Sun Background: Diabetes mellitus (DM) poses a severe threat to global public health. Diabetic nephropathy (DN) is one of the most common complications of diabetes and the leading cause of end-stage renal disease (ESRD...

..., including renal carcinoma, diabetic nephropathy, cystogenesis, and glomerulopathies. Indeed, podocytes, but also the parietal cells of the Bowman capsule are severely affected by miRNA deregulation. In addition, several miRNAs have been found involved in the development of renal fibrosis. These experimental...

...Bancha Satirapoj Background: Diabetes is the leading cause of end-stage renal disease (ESRD) and accounts for 40-50% of patients requiring renal replacement therapy. The main pathophysiology of diabetic nephropathy comprises glucose-dependent pathways, hemodynamic pathways, and genetic factors...

...Yang Liu; Sydney C.W. Tang Background: Diabetic nephropathy (DN) represents the leading cause of end-stage renal disease. Current therapeutic strategies for DN are very limited, and none of them can stop end-stage renal disease progression. Stem cell-based therapy showed encouraging outcomes...

... of the SUMMIT (Surrogate Markers for Micro- and Macro-Vascular Hard Endpoints for Innovative Diabetes Tools) and JDRF-DNCRI (Juvenile Diabetes Research Foundation-Diabetic Nephropathy Collaborative Research Initiative) studies is to combine GWA studies involving more than 25,000 T1DM participants characterized...

...Bancha Satirapoj; Sharon G. Adler Background: Diabetic nephropathy (DN) often results in end-stage renal disease, and this is the most common reason for initiation of dialysis in the United States. Complications of diabetes, particularly renal disease, substantially increase the risk of subsequent...

...Yasuhiko Tomino; Tomohito Gohda Background: Diabetic nephropathy (DN), especially type 2 diabetes, is now increasing rapidly worldwide, also in Asian countries, and is one of the major long-term vascular complications. The pathogenesis of DN involves both genetic and environmental factors. Around...

...Ruijie Liu; Kyung Lee; John Cijiang He Background: Diabetic nephropathy (DN) is the most common cause of end-stage renal disease (ESRD) in the USA and worldwide, contributing to significant morbidity and mortality in diabetic patients. A genetic factor for the development of DN is strongly...