... via intravenous (IV) or intraperitoneal bolus injection. Subsequently, the mice were individually housed in cages covered with plastic wrap. Urine was collected every hour for a total of 3 h for the measurement of urine and sodium excretion. Results: The MAPs for all normotensive mice were consistent...

.... Intrarenal distribution of AQP1 and AQP2 was analyzed by immunohistochemistry. Results: In hypertensive 2K-1C animals, MSC prevented additional increases in BP. AQP1, but not AQP2, was suppressed in the contralateral kidney, resulting in significant increase in urinary flow rate and sodium excretion. Gene...

... from the low-salt to high-salt diet in normotensive salt-sensitive (SS) but not salt-resistant (SR) individuals. There was a significant inverse correlation between the serum GLP-1 level and the MAP in SS subjects. Inverse correlation between the serum GLP-1 level and 24-h urinary sodium excretion...

... elicited similar BP decreases that were associated with increases in daily sodium excretion in 2K1C eNOS+/+ as well as 2K1C eNOS–/– mice. In addition, treatment with the sEH inhibitor increased the ratio of EETs/DHETs in the nonclipped kidney of 2K1C eNOS+/+ as well as 2K1C eNOS–/– mice. Treatment...

... to in the content or advertisements. Sodium excretion ACE inhibition Long-term study Excretion pattern Renal Physiol Biochem 1995; 18:35 48 Willehad Boemke Ülo Palm Rainer Mohnhaupt Marcel Corea Erdmann Seeliger Wolfgang Reinhardt Arbeitsgruppe Experimentelle Anästhesie, Universitätsklinikuni Rudolf...

... increases in sodium excretion and urine flow. Treatment with ouabain when combined with plasma volume expansion increased sodium excretion from 82 ± 30 to 880 ± 203 µmol min -1 and urine flow from 1.9 ± 1.1 to 7.5+1.6 ml min -1 . This combination of treatments results in a synergistic rather than additive...

...Marcel Corea; Erdmann Seeliger; Willehad Boemke; Wolfgang Reinhardt In 5 conscious dogs the diurnal patterns of urinary sodium excretion (U Na V) were investigated, initially during 1 control day and, thereafter, during 4 days of servo-controlled reduction of renal perfusion pressure (rRPP...

...Yan Peng; Carla R. Ramsey; Franklyn G. Knox Previous studies have demonstrated that prostaglandin E 2 (PGE 2 ) infusion increases intrarenal angiotensin-II (ANG-II) formation and decreases sodium excretion in the rat. PGE 2 infusion may have direct tubular effects or indirect effects through...

...John A. Haas; Ali A. Khraibi; Franklyn G. Knox The relationship between fractional sodium excretion (FE Na ) and fractional lithium excretion (FE Li ) was determined in Munich-Wistar rats with intact capsules (control, n = 16), and in rats with acute bilateral renal decapsulation (n = 16) during...

... of fractional sodium excretion and to a decrease of renal oxygen consumption. We conclude that ET-3 is a potent vasoconstrictor in the isolated perfused rat kidney. Furthermore, it modulates GFR in a differentiated mode, depending on the concentration used. The GFR increase at 250 pmol/l ET-3 seems...

...Gibson Oriji; John R. Gill, Jr.; John C.H. Yun; Harry Keiser Renal arterial infusion of acetylcholine (ACh; 40 µg/min) in control dogs produced a sustained rise in urinary sodium excretion (U Na V) and in renal plasma flow (RPF). When prostaglandin (PG) synthesis was inhibited with indomethacin (5...

... Sodium excretion Ureter catheter Renal Physiol Biochcm 1988;11:325-331 © 1988 S. Karger AG. Basel 1011-6524/88/0116-0325 $2.75/0 A New Method for Collecting Urine Directly from the Ureter in Conscious Unrestrained Rats Peter-Joachim Horst, Martin Bauer, Roland Veelken, Thomas Unger Department...

... of 20-HETE and EET formation decreased sodium excretion in HanSD, whereas inhibition of 20-HETE increased urinary excretion of sodium in TGR without altering renal hemodynamics. Conclusions: Our data suggest that in TGR, deficient intrarenal synthesis of EETs combined with increased synthesis of 20-HETE...

..., nitrotyrosine protein expression was assessed by immunoblotting as marker of O 2 – production and urinary 8-epi-PGF 2α excretion as marker of intrarenal oxidative stress was assessed by enzyme immunoassay. Results: BP, glomerular filtration rate (GFR), renal plasma flow (RPF) and sodium excretion were similar...

... reduced both in SHR and Dahl-S rats. In SHR, the amount of sodium excreted was reduced in parallel to the GFR decrease. Sodium excretion was lower in Dahl-S than in Dahl-R due to the former higher Na + tubular reabsorption. The same was true for water excretion and its tubular reabsorption in this strain...

... of angiotensin II (ANG II) in normotensive anesthetized rats. ANG II (6 ng/min, n = 14) decreased glomerular filtration rate (GFR), renal plasma flow (RPF), absolute and fractional sodium excretion by –24 ± 5, –25 ± 6, –44 ± 6 and –28 ± 7%, respectively (p < 0.05). i.r. infusion of Ang-(1–7) (50 ng/min, n...

...Ana D.O. Paixão; Flávia A. Nunes; Claude Léger; Maria L.M. Aléssio The aim of this paper was to study the effects of essential fatty acid (EFA) on fractional sodium excretion (FE Na + ) and renal hemodynamics in rats during hydropenia (H) and acute volume expansion (VE), successively. Mean arterial...