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Keywords: Oxidative stress
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Journal Articles
Journal Articles
Kidney Blood Press Res (2023) 48 (1): 92–101.
Published Online: 02 January 2023
... cells (GECs) and human kidney 2 (HK-2) cells with triplicated wells by using a robotic pipetting workstation to screen for the potential drug candidate. Cell viability and oxidative stress were examined in the GECs and HK-2 cells. DN mouse model was established and treated with 25 mg/kg xanthohumol...
Journal Articles
Journal Articles
Kidney Blood Press Res (2023) 48 (1): 35–44.
Published Online: 08 December 2022
...: The hyperlipidemia rat model was established by feeding with high-fat diet. miR-185-3p and MAML1 levels in hyperlipidemia rats were detected. Adenoviral vectors altering miR-185-3p and MAML1 levels were injected into hyperlipidemia rats to examine the levels of serum lipids, oxidative stress, inflammatory cytokine...
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Journal Articles
Kidney Blood Press Res (2022) 47 (6): 375–390.
Published Online: 03 February 2022
... disorders, the impact of eryptosis on renal anemia demands attention. However, a systemic analysis concerning the pathophysiology of eryptosis has not been expounded. Summary: The complicated conditions in CKD patients, including oxidative stress, osmotic stress, metabolic stress, accumulation of uremic...
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Journal Articles
Journal Articles
Kidney Blood Press Res (2021) 46 (3): 257–265.
Published Online: 28 April 2021
... was established in HK-2 cells, which were pre-treated with or without GYY4137. Renal histology, function, apoptosis, and oxidative stress were measured. Western blot was used to measure the target -protein after renal IRI. Results: The results indicated that GYY4137 had a clear protective effect on renal IRI...
Journal Articles
Kidney Blood Press Res (2019) 44 (5): 1002–1013.
Published Online: 25 September 2019
... mitochondrial damage. In parallel with the SOD2 reduction, the oxidative stress markers of malondialdehyde and HO-1 displayed greater increment in AKI mice with rotenone pretreatment in line with the deteriorated apoptotic response and inflammation. Conclusion: Our results suggested that the inhibition...
Journal Articles
Kidney Blood Press Res (2019) 44 (4): 565–582.
Published Online: 24 July 2019
... (BALF) as well as the wet/dry ratio of the lung were also measured to assess lung injury. Additionally, the effects of miR-203 on inflammatory cytokines, oxidative stress indexes, blood biochemical indexes, serine-threonine protein kinase (AKT) signaling pathway-related factors, and apoptosis-related...
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Journal Articles
Journal Articles
Journal Articles
Kidney Blood Press Res (2018) 43 (3): 651–663.
Published Online: 03 May 2018
... and histopathological changes were observed and evaluated. Additionally, malondialdehyde and glutathione levels were determined in renal tissue homogenate as indicators of oxidative stress. ROS production in cells was determined by DHE staining. Protein biomarker expression was evaluated by western blot, apoptosis...
Journal Articles
Journal Articles
Journal Articles
Journal Articles
Kidney Blood Press Res (2018) 42 (6): 1277–1289.
Published Online: 14 December 2017
.... These changes were accompanied by increased cortical mRNA and protein expression for the renal oxidative stress components including Nox 4 and p22 phox ; ER stress, pro-inflamatory, pro-apoptotic as well as RAS components. ISO also induced a significant increase in medullar renin protein expression. Conclusion...
Journal Articles