...Linlin Fu; Jinliang Ping; Fei Guo; Jiafeng Song; Mingjun Luo; Lijing Chen Introduction: The disruption of podocyte structure and function are the main pathological mechanism of membranous nephropathy (MN). Phospholipases A2, Group XII B (PLA2G12B) was reported involved in the regulation of MN...

...Renata Paula Martins Brandão Paulo; Lectícia Barbosa Jorge; Luis Yu; Viktoria Woronik; Cristiane Bitencourt Dias Introduction: There have been few studies comparing younger and older adults with membranous nephropathy. The objective of this study was to compare younger and older patients...

...Biao Huang; Yi Zhang; Liang Wang; Wenwei Xu; Jue Zhang; Qiuhua Zhang; Huiming Sheng; Zhigang Hu Aims: The aim of this study was to develop a new method for detecting anti-phospholipase A2 receptor-IgG4 to improve the sensitivity and specificity in the diagnosis of idiopathic membranous nephropathy...

... the patients who developed focal segmental glomerulosclerosis (FSGS; n = 13), IgA nephropathy (IgAN; n = 10), IgAN with morphological presentation of focal segmental glomerulosclerosis (IgAN/FSGS; n = 8), membranous nephropathy (MN; n = 12), and lupus nephritis (LN; n = 6) were included in the analysis. We...

... locus. In African Americans, much of the risk for end-stage nondiabetic kidney disease is explained by common variants in the MYH9/APOL1 locus, and in individuals of European descent, variants in HLA-DQA1 and PLA 2 R1 implicate most of the risk for idiopathic membranous nephropathy. In contrast, genetic...

...Ilona Idasiak-Piechocka; Andrzej Oko; Katarzyna Łochyńska-Bielecka; Beata Skrobańska Aim: This observational study aimed to evaluate the results of treatment with low-dose chlorambucil in combination with corticosteroids in patients with idiopathic membranous nephropathy (iMGN) and nephrotic...