... lymphatic endothelial cells (LECs) increase in response to HTN and that augmenting lymphangiogenesis in the kidneys reduces blood pressure and renal pro-inflammatory immune cells in mice with various forms of HTN. Our aim was to evaluate the specific changes that renal LECs undergo in HTN. Methods: We...

...Lisa-Maren Fischer; Laura A. Fichte; Maike Büttner-Herold; Fulvia Ferrazzi; Kerstin Amann; Kerstin Benz; Christoph Daniel Objective: Complement deposition is prevalent in kidney biopsies of patients with arterial hypertension and hypertensive nephropathy, but an association of hypertension...

...). Caspase-3 activity was measured by a caspase-3 colorimetric assay kit (Keygen Biotech Co., Ltd., Shanghai, China) according to the manufacturer’s instructions. gao666332@sina.com 15 02 2020 5 07 2020 28 4 2021 Acute kidney injury (AKI) is a common complex clinical...

... analyzed in stereological studies of the kidney. However, there is no consensus about if the PCT and DCT should be considered circular or elliptical in shape. Objective: To analyze if there are significant differences in the diameter and area of the PCT and DCT, depending on whether they are considered...

... increase local angiotensin-converting enzyme 2 ( ACE2 ) expression. Methods: In this study, we evaluated the effect of ACEi or ARB treatment on expression of ACE2 , ACE , and AGTR1 in 3-month protocol kidney allograft biopsies of stable patients using RT-qPCR ( n = 48). Protein ACE2 expression was assessed...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Angiotensin-converting enzyme inhibitors Hypertension Kidney Systemic...

..., which is strongly associated with renal prognosis in diabetic kidney disease (DKD). Therefore, urinary markers that can detect renal hypoxia are useful for monitoring DKD. Objective: To determine the correlation between urinary liver-type fatty acid-binding protein (L-FABP) and renal hypoxia using...

... or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Calcium oxalate Kidney...

...Roger Gaspar Marchon; Carina Teixeira Ribeiro; Waldemar Silva Costa; Francisco José Barcellos Sampaio; Marco Aurélio Pereira-Sampaio; Diogo Benchimol de Souza Background/Aims: Stress had been related to physiological and morphological alterations in different organs, however kidney morphology...

... used method for BOLD analysis. In the last 20 years, many investigators have used this method to evaluate cortical and medullary oxygenation in patients with ischemic nephropathy, hypertensive nephropathy, diabetic nephropathy, chronic kidney disease (CKD), acute kidney injury and renal allograft...

...Joshua Rowland; Artur Akbarov; Akhlaq Maan; James Eales; John Dormer; Maciej Tomaszewski Ageing of the kidney is a multi-dimensional process that occurs simultaneously at the molecular, cellular, histological, anatomical and physiological level. Nephron number and renal cortical volume decline...

... study with 28 participants including 9 subjects with ATN-induced acute kidney injury (AKI), 9 healthy controls, and 10 subjects with nephron sparing tumor resection (NSS) with clamping of the renal artery serving as a model of ischemia/reperfusion (I/R)-induced subclinical ATN (median clamping time 15...

...Saeed Alshahrani; Manoocher Soleimani Background/Aims: The Cl - /HCO 3 - exchanger pendrin and the thiazide-sensitive Na-Cl cotransporter NCC are expressed in the kidney distal nephron and mediate salt absorption. We hypothesized that deletion of pendrin leaves NCC as the major salt absorbing...

.... Biomarker Chronic kidney disease EGF Epidermal Growth Factor Fibrosis Glomerulonephritis Kidney NGAL Neutrophil gelatinase-associated lipocalin MCP-1 Monocyte chemoattractant protein-1 Tubulointerstitial Chronic kidney disease (CKD) is an important cause of morbidity and mortality...

... suggest that renalase reflects kidney functioning. A common missense polymorphism in the flavin-adenine dinucleotide-binding domain of human renalase (Glu37Asp) has been described. In this study we examined the association between (Glu37Asp) polymorphism (rs2296545) in renalase gene and kidney allograft...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Energy depletion Phosphate transport Compound C Kidney The AMP-activated protein kinase (AMPK) senses the cytosolic AMP/ATP concentration ratio and thus the energy status...

...Ramazan Altintas; Hakan Parlakpinar; Ali Beytur; Nigar Vardi; Alaadin Polat; Mustafa Sagir; Gul Pelin Odabas Background/Aims: This experimental study was designed to investigate protective and therapeutic effects of Dexpanthenol (Dxp), an alcoholic analogue of pantothenic acid, on kidney damage...

...-1 stimulates glucose-dependent insulin secretion from pancreatic beta-cells and suppresses glucagon release from alpha-cells, thereby improving glucose control. Besides its action on the pancreas type 1 glucagon like peptide has direct effects on the heart, vessels and kidney mainly via the type 1...

...Jana Henschkowski; Heike A. Bischoff-Ferrari; Rudolf P. Wüthrich; Andreas L. Serra Background and Aim: Cinacalcet effectively reduces calcium in patients with persistent hyperparathyroidism (HPT) after kidney transplantation. We aimed to assess the association of cinacalcet with a decrease in renal...

... nephropathy. In contrast, elevated UMOD excretion may be associated with, and thus predictive of, chronic kidney disease. UMOD analysis is therefore of importance in all conditions with renal involvement and may be useful in the proper classification of renal diseases. 25 11 2010 © 2010 S. Karger...