... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Acute kidney injury Renal ischemia-reperfusion injury miRNA RNA methylation Immune cell infiltration Inflammation Acute kidney injury (AKI) often occurs...

...Qin Zhou; Xiaofei Shao; Li Xu; Hequn Zou; Wenli Chen Introduction: Inflammation plays a key role in chronic kidney disease (CKD). Monocyte-to-lymphocyte ratio (MLR) is a novel inflammatory marker. The purpose of this study was to evaluate the relationship between MLR and inflammation in CKD...

...Justin G. McDermott; Bethany L. Goodlett; Heidi A. Creed; Shobana Navaneethabalakrishnan; Joseph M. Rutkowski; Brett M. Mitchell Introduction: Hypertension (HTN) is a major cardiovascular disease that can cause and be worsened by renal damage and inflammation. We previously reported that renal...

...Ming Yang; Jiayi Lv; Chanjuan Gong; Cheng Xue; Lili Fu; Shunjie Chen; Changlin Mei Introduction: It has been reported that rapamycin inhibited inflammation in renal interstitial diseases. We therefore hypothesized that rapamycin could attenuate inflammation in polycystic kidney disease (PKD...

..., including serum creatinine, kidney weight/body weight, urine volume, total proteins, and albumin in the urine, and increased creatinine clearance. Periodic acid-Schiff staining also indicated that α-NETA could effectively ameliorate renal injuries in DN mice. In addition, α-NETA inhibited renal inflammation...

... with chronic inflammation. Neutrophil-lymphocyte ratio (NLR) is an inflammatory marker that was shown to correlate with CV outcomes. However, little is known about the significance of serial monitoring of serum NLR. We aimed to determine the prognostic value of serial NLR on all-cause mortality and CV...

... the Gd-IgA1 levels in both blood and urine specimens. C57BL/6 mice were given a broad-spectrum antibiotic cocktail to deplete the endogenous gut flora. We established a model of IgAN in pseudosterile mice and investigated the expression of the markers of intestinal permeability, inflammation, and local...

...Yuqi Yang; Jingjing Da; Qian Li; Yanjun Long; Jing Yuan; Yan Zha Introduction: Cognitive impairment is prevalent in patients undergoing hemodialysis (HD), which is related to the nutritional and inflammatory status of this population. Malnutrition-inflammation score (MIS) has been identified...

...Paulo C. Gregório; Gilson Biagini; Regiane S. da Cunha; Júlia Budag; Ana Maria Martins; Lara Valiño Rivas; Elberth M. Schiefer; Maria Dolores Sánchez-Niño; Alberto Ortiz; Andréa E. M. Stinghen; Fellype C. Barreto Background and Aims: Inflammation and endothelial damage play a pivotal role in Fabry...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Idiopathic and secondary retroperitoneal fibrosis Inflammation...

... the expression of NLRP3 as well as the expressions of caspase-1 and interleukin-1β. Either miR-34c inhibition or NLRP3 overexpression could reverse the accentuation of pyroptosis and inflammation by sh-NEAT1 transfection in the in vitro model of DN. Conclusions: Our findings suggested NEAT1 and its target gene...

.... Inflammation Renal failure Cardiovascular disease End stage renal disease (ESRD) is a serious and costly medical problem [ 1, 2 ]. Peritoneal dialysis (PD) is a life-saving treatment of ESRD and being a home-based and inexpensive modality of dialysis, the utilization of PD has been increasing in many...

... between both systems possible. In general, this communication down-regulates the inflammation, achieved through different mechanisms and depending on the cells involved. Summary: With the awareness that the cholinergic anti-inflammatory pathway serves to prevent or limit inflammation in peripheral organs...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Chronic kidney disease Estimated glomerular filtrate rate Geriatrics Geriatric syndrome Hypoalbuminemia Inflammation Malnutrition Chronic kidney disease (CKD...

... of the most common metabolic disorders. Emerging evidence indicates that autophagy and inflammatory responses are related to the formation of CaOx nephrolithiasis. However, the roles of autophagy and inflammation in patients with hypercalciuria remain unclear. Ethyl pyruvate (EP) displays protective effects...

..., mice were administered with APAP (300mg/kg) by intraperitoneal injection for 24 h. Then the kidney injury, inflammation, and oxidative stress were evaluated. Results: APAP significantly enhanced the BUN, serum creatine, and cystatin C levels in line with a moderate alteration of renal morphology...

... of inflammation and oxidative stress following ischemic organ injury. We tested the hypothesis that activation of TRPV1 conveys preconditioning protection to the kidney subjected to I/R. Methods: TRPV1 was activated or down-regulated by subcutaneous injection of a low (1mg/kg) or high (100mg/kg) dose of capsaicin...

... and creatinine levels. Furthermore, we observed that NADPH increased glutathione levels, while reducing levels of malondialdehyde and reactive oxygen species. Additionally, our results suggested that NADPH treatment may alleviate IRI-induced apoptosis and inflammation. Conclusion: NADPH treatment may protect...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Acute kidney injury Cisplatin Endothelium Inflammation Physical training Acute kidney injury (AKI) is known...

...Katarzyna Muras-Szwedziak; Michal Nowicki Background/Aims: Both iron deficiency and chronic inflammation are highly prevalent in patients with chronic kidney disease (CKD). The effect of intravenous iron infusion on mineral metabolism in CKD may be modified by inflammation. Intravenous iron...