...Justin G. McDermott; Bethany L. Goodlett; Heidi A. Creed; Shobana Navaneethabalakrishnan; Joseph M. Rutkowski; Brett M. Mitchell Introduction: Hypertension (HTN) is a major cardiovascular disease that can cause and be worsened by renal damage and inflammation. We previously reported that renal...

...Bartosz Symonides; Maria Zaborska-Dworak; Jacek Lewandowski; Wojciech Marcinkowski; Jacek Zawierucha; Tomasz Prystacki; Jolanta Małyszko Introduction: The prevalence of hypertension among patients with end-stage kidney disease (ESKD) undergoing hemodialysis (HD) ranges from 72 to 88% depending...

...; Andrés Felipe Buitrago; Jorge Alberto Sandoval-Luna; Clara Saldarriaga; Juan Esteban Gómez-Mesa Introduction: Arterial hypertension represents one of the main comorbidities observed in patients with heart failure (HF) and one of the main risk factors for its development. Despite this, studies assessing...

... a novel method that enables AVE to be conducted in conscious mice. Methods: We have implemented this innovative approach in two animal models representing either intact or impaired renal function, specifically utilizing a lower nephron hypertensive model. Mice were implanted with radio-transmitters...

...Jessica Liberona; Patricio Araos; Marcelo Rodríguez; Pablo León; Andrés Stutzin; Rodrigo Alzamora; Luis Michea Introduction: A comprehensive pathophysiological mechanism to explain the relationship between high-salt intake and hypertension remains undefined. Evidence suggests that chloride...

... (PC1) and polycystin-2 (PC2), respectively. The presence of kidney cysts is a characteristic feature in the ADPKD patients. But in the ADPKD patients, cardiovascular abnormalities, such as hypertension (HT) with higher systolic blood pressure (SBP) and diastolic blood pressure (DBP) values, higher left...

..., the impact of the direct renin inhibitor as monotherapy has not been assessed. Here, we investigated the effects of 24-week monotherapy with aliskiren compared to amlodipine in hypertensive patients with type 2 diabetes or obesity. Methods: In this randomized intervention study, 62 adult hypertensive...

... hypertension, it is unknown if the values of systolic blood pressure (SBP) considered in control (<120 mm Hg) are associated with kidney replacement therapy (KRT) and mortality. Methods: In this retrospective cohort study, hypertensive CKD stages 4–5 patients attending the Renal Health Clinic...

... with the increase in homocysteine levels, both significantly. Multivariate stepwise regression analysis showed that eGFR and homocysteine were independently associated with LVMI in patients with hypertension. No correlation was observed between homocysteine and LVMI in patients without hypertension. Stratified...

...Stephanie Thompson; Natasha Wiebe; Michael K. Stickland; Gabor T. Gyenes; Rachelle Davies; Jeff Vallance; Michelle Graham Introduction: Exercise is an effective strategy for blood pressure (BP) reduction in the general population, but its efficacy for the management of hypertension in chronic...

...Yunlong Qin; Jin Zhao; Yuwei Wang; Ming Bai; Shiren Sun Background: China has the largest absolute burden of hypertension (HTN) in the world. Gut dysbiosis may be a potentially modifiable risk factor for HTN. However, the characteristics of gut microbiota in Chinese populations with HTN remain...

...Xiaoxv Yang; Hui Liu; Shifang Chen; Pingshuan Dong; Di Zhao Background: This meta-analysis was designed to evaluate the antihypertensive efficacy of intravascular renal denervation (RDN) in patients with essential hypertension, especially to determine the magnitude of blood pressure (BP) reduction...

... and that abundance is strongly impacted by haemodialysis. The technique described here could readily be applied to other clinical situations where sodium pump inhibition might be anticipated, such as hypertension, pregnancy, and foetal medicine, and thereby lead to a better understanding of the physiology...

... of hypertension induced by a high-fat diet and to explore possible molecular mechanisms. Methods: Twenty-four Bama miniature pigs were randomly divided into a control group (normal diet, n = 6) or a hypertension model group (high-fat diet, n = 18). The model group was randomly divided into the intima-RDN group...

...Chengdong Yu; Xiaolan Ren; Li Pan; Hongjun Zhao; Ye Wang; Lijun Chang; Huijing He; Jin’en Xi; Guangliang Shan Introduction: Serum uric acid (SUA) has been found correlated with an increased risk of hypertension, but evidence is sparse regarding the association in Gansu Province, especially in Yugur...

...Zhubin Lun; Ziling Mai; Liwei Liu; Guanzhong Chen; Huanqiang Li; Ming Ying; Bo Wang; Shiqun Chen; Yongquan Yang; Jin Liu; Jiyan Chen; Jianfeng Ye; Yong Liu Objective: Previous studies have shown that the relationship between hypertension (HT) and contrast-associated acute kidney injury (CA-AKI...

...Jia Zhou; Dingkun Wang; Bingong Li; Xuelian Li; Xingjun Lai; Shufang Lei; Na Li; Xuting Zhang Introduction: Trimethylamine N-oxide (TMAO) is a metabolite produced by gut bacteria. Although increased TMAO levels have been linked to hypertension (HTN) and chronic kidney disease (CKD) with poor...

...Lisa-Maren Fischer; Laura A. Fichte; Maike Büttner-Herold; Fulvia Ferrazzi; Kerstin Amann; Kerstin Benz; Christoph Daniel Objective: Complement deposition is prevalent in kidney biopsies of patients with arterial hypertension and hypertensive nephropathy, but an association of hypertension...

...Anna Chudek; Aleksander Jerzy Owczarek; Joanna Ficek; Magdalena Olszanecka-Glinianowicz; Katarzyna Wieczorowska-Tobis; Zofia Walencka; Agnieszka Almgren-Rachtan; Jerzy Chudek Background: Gender-related differences in fat distribution may affect blood pressure (BP) control in hypertensive subjects...

...Yong-Chang Duan; Lin Shi; Zheng Jin; Meng Hu; Hao Huang; Tao Yan; Kun-Ru Zhang Background: Hypertensive nephropathy is one of the major causes of ESRD. Exercise has been considered a nonpathological therapy for hypertension and its complications, yet mechanisms remain unclear. We sought...