...Alieh Gholaminejad; Maryam Ghaeidamini; Jesus Simal-Gandara; Amir Roointan Background: Focal and segmental glomerulosclerosis (FSGS) is a clinical-pathologic condition marked by segmental and localized glomerular damages. Despite investigations, the molecular mechanisms behind FSGS development...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Rac1 GTPase Membrane rafts Inflammatory machinery Glomerulosclerosis Reactive oxygen species...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Danhong injection Glomerulosclerosis Hypertension Kidney injury...

... fatty acids (FFA). Results: Compared with the chow diet group, HFD-fed WT mice had higher urinary albumin and increased levels of renal fibrosis, glomerulosclerosis, inflammation, oxidative stress and apoptosis in the kidney. These changes were co-related with increased expression of TNF-α in the kidney...

... number Heart Urinary production Albuminuria Glomerulosclerosis Renal vasculature Tubular transporter High salt Table 1 Animal data - Body weight, kidney weight and serum parameters Table 2 Animal data - Urinary parameters High salt diet increased diuresis...

... of glomerulosclerosis and tubulointerstitial fibrosis was determined by Masson’s trichrome stain. Renal expression of ED-1, transforming growth factor-β1 (TGF-β1), Bax, and Bcl-2 were determined by semiquantitative immunoblotting, polymerase chain reaction (PCR), and immunohistochemistry. TUNEL staining was used...

.../6 NX and a 20-min EA-MO session in three real acupuncture points. The treatment consisted of 16 sessions twice a week. Renal function, urine volume, serum creatinine, 24-hour proteinuria, direct and indirect blood pressure, glomerulosclerosis and tubulointerstitial fibrosis indices were assessed...

...Takanobu Sakemi; Noriaki Ohtsuka; Yoshiyuki Tomiyoshi; Fumitaka Morito Hypercholesterolemic Imai rats spontaneously develop proteinuria and glomerulosclerosis, especially males. Estrogen attenuates the progressive glomerular injury in these male rats. To clarify whether this attenuating effect...

... on the renal function with regard to blood urea nitrogen (BUN), serum creatinine (Cr) and Cr clearance (Ccr) levels, but a combined treatment with OVX and T significantly lowered the serum albumin levels, increased the levels of BUN and Cr and lowered the Ccr values. The glomerulosclerosis index...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Angiotensin, generation Chronic renal failure, angiotensin Glomerulosclerosis...

... for potential anti-inflammatory treatment approaches selectively targeting iNOS overexpression. Nitric oxide Glomerulonephritis L -Arginine Inflammation Macrophages Cytokines Glomerulosclerosis Tissue injury Hypertension © 1996 S. Karger AG, Basel 1996 Copyright / Drug Dosage / Disclaimer...

... Nephrogenesis Glomerular number Kidney function Glomerular hyperfiltration Glomerulosclerosis Renin-angiotensin system Nitric oxide Insulin-like growth factor I the RAS at an early stage in order to prevent the compensatory glomerular hyperfiltration, but this is far from being applicable...

...Yuji Ikeda; Takanobu Sakemi; Yoshiyuki Tomiyoshi; Motoaki Miyazono Hypercholesterolemic Imai rats spontaneously develop proteinuria and glomerulosclerosis, especially male animals. Ovariectomy aggravates glomerular injury in femal Imai rats. However, estrogen replacement therapy did not abolish...

...) chow on proteinuria, renal blood flow and glomerular morphology were evaluated in Milan normotensive rats that spontaneously develop progressive glomerulosclerosis. Methods: Eight rats each were pairfed FO– versus cholesterol–enriched or control diets for either 2 or 32 weeks. 4/48 animals died (2–week...

...Shaoming Huang; Roland M. Schaefer; Stefan Reisch; Leszek Paczek; Liliana Schaefer; Markus Teschner; Katarina Sebekova; August Heidland Glomerulosclerosis and tubulointerstitial fibrosis are the hallmarks of chronic renal diseases. In the present study, we have investigated the potential...