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1-2 of 2
Keywords: ENaC
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Journal Articles
Journal:
Kidney and Blood Pressure Research
Kidney Blood Press Res (2013) 37 (4-5): 514–520.
Published Online: 16 November 2013
... + channel ENaC and thus colonic sodium absorption. At least in theory, inflammatory bowel disease in JAK3-deficient mice could lead to intestinal salt loss compromizing extracellular volume maintenance and blood pressure regulation. The present study thus explored whether JAK3 deficiency impacts on colonic...
Journal Articles
Hyun-Seok Jin, Kyung-Won Hong, Ji-Eun Lim, Sue-Yun Hwang, Sang-Ho Lee, Chol Shin, Hun Kuk Park, Bermseok Oh
Journal:
Kidney and Blood Pressure Research
Kidney Blood Press Res (2010) 33 (1): 15–23.
Published Online: 15 January 2010
... channel protein (ENaC: protein complex of SCNN1A, SCNN1B, and SCNN1G). The surface expression of ENaC components is directed by the ubiquitination of ENaC by NEDD4L, an ENaC-specific E3 ubiquitin ligase, and is regulated by the deubiquitination of ENaC by USP2. The activity of NEDD4L in turn is regulated...