... older (median age 59 vs. 40 years) than No-NODM patients. Baseline fasting blood glucose levels were slightly higher in the NODM group; however, the difference was not significant ( p = 0.07). Older age was an independent risk factor for NODM (OR 1.73 and 95% CI 1.20–2.47, p = 0.003). Overall kidney...

...Joshua Rowland; Artur Akbarov; Akhlaq Maan; James Eales; John Dormer; Maciej Tomaszewski Ageing of the kidney is a multi-dimensional process that occurs simultaneously at the molecular, cellular, histological, anatomical and physiological level. Nephron number and renal cortical volume decline...

... baseline ADMA, advanced glycation end products (AGE), and advanced oxidation protein products (AOPP) compared with controls (P<0.001). In a total of 164 patients who completed a one-year study, the estimated GFR (eGFR) declined from 23.5 (17.7-36) mL/min/1.73m 2 to 21 (14.7-31.5) (P=0.018), AGE rose...

... with increasing age in hemodialysis patients. Methods : We retrospectively analyzed 2,174 patients on hemodialysis from March 2005 to December 2012. The impact of intradialytic and interdialytic BP variability on all-cause mortality according to age groups was analyzed. Results: Kaplan-Meier survival curves for 5...

... male and female TGR, and no effect of castration on plasma and tissue ANG II levels was found either in male or female TGR at the end of the experiment. In conclusion, the contribution of the renin-angiotensin system to the gender difference in BP homeostasis seems to be negligible in aging...

... at normotensive pressure (110 mm Hg). In adult (12-week-old) rats, no significant change in either parameter of kidney function was found in the two strains. In contrast, substantial changes were observed in both strains at the age of 6 weeks. Glomerular filtration rate and filtration fraction were similarly...