... these agents in vivo. We have therefore modified a rat vena cava model of venous thrombosis based upon vascular injury and stasis. Wistar rats are anaesthetised, the inferior cava dissected free and a segment isolated by slings distally above the iliacs and proximally above the left renal vein. All other...

.... In the rat vena cava, they are of the 5-HT 1B subtype, in the pig coronary artery they belong to a novel, so far unknown class of 5-HT receptors, and in the human saphenous vein they could be classified as 5-HT 1D . These results point to marked species differences and the need to carry out experiments...

...Tomohiro Ichikawa; Naohisa Ishikawa; Tatsuro Shigei The innervation of three embryologically distinct segments of the canine inferior vena cava was investigated. These segments were termed A (supradiaphragm), B-C (intrahepatic and that between liver and renal veins), and D (infrarenal). Strips were...

...Tatsuro Shigei; Naohisa Ishikawa; Tomohiro Ichikawa; Hiromichi Tsuru The canine posterior vena cava was excised and divided into three embryologically distinct segments: segment A (supradiaphragm), segment B-C (intra-hepatic and that between liver and renal veins), and segment D (infrarenal...

...Roberto F. Nicosia; Wen-Hui Zhu; Eric Fogel; Karen M. Howson; Alfred C. Aplin Explants of rat inferior vena cava embedded in collagen gel and cultured under serum-free conditions produced microvascular outgrowths composed of endothelial cells and pericytes. Exogenous vascular endothelial growth...