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Keywords: Transcription
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Journal Articles
Heparin Regulates Transcription of Endothelin-1 Gene in Endothelial Cells
Available to PurchaseKazue Kuwahara-Watanabe, Chiaki Hidai, Hiromi Ikeda, Yoshikazu Aoka, Ken-ichiro Ichikawa, Nobuo Iguchi, Masako Okada-Ohno, Jinko Yokota, Hiroshi Kasanuki, Masatoshi Kawana
Journal:
Journal of Vascular Research
J Vasc Res (2005) 42 (3): 183–189.
Published Online: 03 June 2005
... in animals and humans. These effects are mediated by the inhibition of endothelin-1 (ET-1) production in endothelial cells. To clarify the mechanism of this inhibition, we investigated the effect of heparin on transcriptional regulation of the ET-1 gene in bovine aortic endothelial cells (BAEC) cultured...
Journal Articles
Regulation of Matrix Metalloproteinase (Matrixin) Genes in Blood Vessels: A Multi-Step Recruitment Model for Pathological Remodelling
Available to Purchase
Journal:
Journal of Vascular Research
J Vasc Res (2003) 40 (4): 329–343.
Published Online: 26 September 2003
... of multiple signalling pathways leading to co-operative action of several transcription factors on the MMP promoters. Four levels of control of MMP activity have been distinguished, namely induction of new proteases, regulation of secretion of stored proteases, proteolytic activation of protease pro-forms...
