... to acetylcholine at either temperature. At 37 and 24 °C, the inhibitor of low conductance calcium-activated potassium channels apamin (10 –7 M ), the inhibitor of ATP-dependent potassium channels glibenclamide (10 –5 M ) and the cyclooxygenase inhibitor meclofenamate (10 -5 M), alone or combined with L-NAME, did...

... temperatures. Arteries have predominantly α 1 -adrenoceptors and veins have predominantly receptors of the α 2 -type. We obtained dose-response curves to NE at 9, 16, 23, 30, 37 and 42 °C in the absence and presence of the irreversible α -adrenoceptor blocker phenoxybenzamine (POB). In both vessels, affinity...

...). The accumulation of 3 H derived from 3 H-A (10–8 M; 1 h) was dependent on the bath temperature (1–37 °C). The accumulation increased continuously from 1.1 ml·g –1 (1 °C) to 11.1 ml·g -1 (37 °C). Storage of tissue (0–5 days in salt solution without equilibration with 95% O 2 /5% CO 2 ; 4 °C) did not affect...

... of cooling in basal conditions and during the different forms of increased overflow of adrenergic transmitter suggest that lowering the temperature inhibits the exocytotic process, but at the same time slows down the diffusion of norepinephrine from the junctional cleft to the extracellular space...

...) for varying periods at 37 or 0 °C. The 3 H-CA accumulation was 1.3 ml/g at 0 °C and 2.2 ml/g at 37 °C. The sorbitol space was 0.6 ml/g at both temperatures. CA accumulation at 0 and 37 °C is significantly different from each other and from sorbitol accumulation. Corticosterone and phenoxybenzamine inhibit...

... neurotransmission. It probably is due to an altered sensitivity of the vascular smooth muscle to the transmitter. Temperature Adrenergic neurotransmission Local cooling Vascular smooth muscle Cutaneous veins Nerve stimulation © 1976 S. Karger AG, Basel 1976 Copyright / Drug Dosage / Disclaimer...

...Noboru Toda; Masakazu Hojo; Koichiro Sakae Contractile responses of helically-cut strips of the rabbit aorta to drugs, ions and transmural electrical stimulation were compared at different temperatures of the bathing medium, the response at 37 °C being taken as control. The dose-response curve...