...Régent Laporte; Ismail Laher A characteristic of vascular smooth muscle cell morphology is a close apposition of its peripheral sarcoplasmic reticulum (SR) with the sarcolomma; this arrangement gives rise to important functional interactions whereby the peripheral SR regulates Ca 2+ influx...

...-Brown Cardiovascular Research and Training Center of the Methodist Hospital, Houston, Tex. Key Words. Aorta Smooth muscle Relaxation . Sarcoplasmic reticulum Microsomes . Ca*+ binding and release Cyclic AMP Abstract. Ca** binding to a microsomal fraction from canine aorta has been studied...

... patch clamp studies [ 25 ]. All lipid bilayer experiments were performed at room temperature about 20°C. Posttranslational modification Ca 2+ mobilization Sarcoplasmic reticulum Vascular smooth muscle Coronary artery Using this bilayer preparation, the effects of SAM on the activity...

... , DNA content, and SR distribution in SMCs from organ culture indicated that the UTP-induced Ca m increase occurred exclusively in SMCs that had a dedifferentiated cell phenotype. Three-dimensional image reconstruction of the nucleus and sarcoplasmic reticulum (SR) revealed a novel transnuclear SR...