... (CABG) success rates, preserving saphenous vein endothelium during surgery may improve patency. Standard preparations include saphenous vein preparation in heparinized saline (saline) which can result in endothelial loss and damage. Here, we investigated the impact of preparing saphenous graft vessels...

...Markus Hoenicka; Marius Sabau; Andreas Liebold; Hans-Stefan Hofmann; Michael Ried Introduction: Adrenoceptor and endothelin (ET) receptor-mediated vasoconstriction as well as endothelium-dependent vasodilation of human saphenous veins were compared before and after 20 h of cold storage. Methods...

...Lesley Scott; Alan Kerr; David Haydock; Mervyn Merrilees Coronary bypass vessels, saphenous vein (SV) and internal thoracic artery (ITA), differ in susceptibility to atherosclerosis and medium- to long-term patency. Whereas most ITA remain patent (90% at 10 years), 20% of SV grafts fail...

.... In the rat vena cava, they are of the 5-HT 1B subtype, in the pig coronary artery they belong to a novel, so far unknown class of 5-HT receptors, and in the human saphenous vein they could be classified as 5-HT 1D . These results point to marked species differences and the need to carry out experiments...

...Stig Steen; Roger Willén; Trygve Sjöberg; Birgitta Carlén Research Papers Blood Vessels 1991;28:349-353 © 1991 S. Karger AG, Basel 0303-6847/91/0285-0349S2.75/0 Contractile and Morphologic Properties of a Saphenous Vein after 12 Years as an Aortocoronary Bypass Graft Stig Steen, Roger Willen...

...Robert S. Crissman Stereo scanning electron microscopy was used to study the normal arrangement of elastic fibers in canine saphenous veins. Selective alkali digestion and autoclaving exposed a network of interconnecting elastic fibers throughout the venous wall. 14 normal saphenous veins were...

... mN/mm 2 at 15 s. Like other smooth muscles, in general, saphenous vein develops considerable isometric tension and has a high shortening capacity but a low shortening velocity. The reduction in shortening velocity that occurs after 5 s in an isometric contraction is probably due to the development...

...J. Garrett; J. Castro-Tavares; D. Branco Tissue noradrenaline content as well as uptake and metabolism of tritiated exogenous noradrenaline were studied comparatively, in vitro in mesenteric arteries, and in saphenous veins of normotensive and perinephritic hypertensive dogs. The influence...

...A. Coimbra; A. Ribeiro-Silva; W. Osswald The tunica media of the dog lateral saphenous vein contains 8–12 layers of predominantly circular smooth muscle fibers. Numerous nerve profiles exhibit bright green fluorescence after formaldehyde gas treatment. These profiles occur amongst the muscle cells...

...Fernando Brandão The aim of this study was to determine the relative importance of neuronal uptake, catechol-O-methyltransferase (COMT) and diffusion in the disposition of endogenous noradrenaline (NA) in the rabbit aorta and dog saphenous vein. Helical strips of dog saphenous vein and rabbit aorta...

...Martin F. Crook; Kay M. Southgate; Andrew C. Newby Atherosclerosis underlies late occlusion of human saphenous vein (HSV) coronary artery bypass grafts. Monocyte infiltration is implicated, but its mechanisms are unclear given that HSV normally expresses the ICAM-1 but not the VCAM-1 adhesion...

...David Kachlik; Vaclav Baca; Josef Stingl; Bohumil Sosna; Alois Lametschwandtner; Bernd Minnich; Marek Setina Objective: The detailed spatial arrangement of the vasa vasorum (VV) of the human great saphenous vein (HGSV) was demonstrated in qualitative and quantitative terms. Materials and Methods...

...Sarah J. George; Jason L. Johnson; Melanie A. Smith; Gianni D. Angelini; Christopher L. Jackson Background: The effect of activation of endogenous transforming growth factor-β (TGF-β) on smooth muscle cell apoptosis was assessed in human saphenous vein. Methods: Segments of human saphenous vein...

...Sarah J. George; Jason L. Johnson; Melanie A. Smith; Christopher L. Jackson The focus of this study was identification of the contribution of the plasminogen activator-plasmin system to smooth muscle cell proliferation and migration in human saphenous vein. Segments of human saphenous vein were...

... the effects of diadenosines on primary cultures of human saphenous vein endothelial cells (HSVECs) and related this to the expression of P2Y receptors. HSVECs were loaded with the calcium-sensitive dye fura-2, and nucleotide-stimulated [Ca 2+ ] c responses were recorded. HSVECs responded to 10 µ M UTP, ATP...