... Endothelium Endothelin isopeptides ECE ETA/ETB receptors Signal transduction Phospholipase C Ca2+ channel Protein kinase C Phospholipase D Phospholipase A2 Adenylate cyclase Guanylate cyclase Nuclear signalling Abstract Endothelin (ET)-l, an endothelium-derived vasoactive polypeptide encoded in the human...

... or topical acetylcholine (10 -5 M), but responses to norepinephrine (10-5 M) and sodium nitroprusside (1 0 '4 M) were unaltered. Indomethacin, theophylline or propranolol did not affect the flow-induced dilation. Quinacrine, an inhibitor o f phospholipase A2, attenuated the dilation response in a dose...

... Phospholipid cycle Phospholipase C Phospholipase A2 Shear stress Inositol triphosphate Diacylglycérol Arachidonic acid Endothelial cell Abstract There is evidence suggesting that fluid shear stress activates phospholipid turnover in endothelial cells, but it is not clear which phospholipids are involved...

... phospholipase A2. J Leukoc Biol 1998;64:221–227. 7. Zeng L, An S, Goetzl J: Regulation of expression of matrix metalloproteinase-9 in early human T cells of the HSB.2 cultured line by the EP 3 subtype of prostaglandin E 2 receptor. J Biol Chem 1996;271:27744–27750. 8. Kanse SM, Benzakour O, Kanthou C...