...P.H. Carpentier Vasomotion is a potential target for drugs in vascular diseases. In this work, the effects on arteriolar vasomotion of norepinephrine, phentolamine and the vasoactive drug buflomedil were assessed in the hamster skinfold preparation. Results show the strong vaso-kinetic properties...

... characteristics. The relative sympathomimetic potency suggested α-adrenergic receptors, which was confirmed in Schild plots following phentolamine antagonism of the response (pA 2 for artery 7.57, for vein 7.75). 5-HT contracted with a relative potency approximately equal to noradrenaline and adrenaline...

...Robert R. Ruffolo, jr.; Popat N. Patil The rates of onset and offset of α-adrenoreceptor blockade by phentolamine (5 × 10 -7 M ) have been studied on the normal and denervated rabbit aorta and rat vas deferens. Removal of the adventitia with its accompanying sympathetic nerve component results...

...Ove A. Nedergaard; Jørgen Schrold The effect of atropine on the electrical-field stimulation-evoked overflow of tritium from isolated rabbit pulmonary arteries preincubated with 3 H-noradrenaline was studied. Atropine (10 –4 M ) and phentolamine (10 –6 M ) increased stimulation-induced overflow...

... cell types and their released amines and ATP. Electrical field stimulation which affects the nerve terminals does not change the ultrastructure of the mast cells unless the α-blocking agent phentolamine (7.5 × 10 -7 M) is present during the stimulation, when degranulation results. 12 03 1979 1...

... to potassium, while the sensitivity to NE (NE-ED 50 = 0.4 µM ) was about the same as the NE sensitivity reported for larger human vessels. The sensitivity to NE was unaffected by cocaine, while the response to potassium was unaffected by phentolamine. Fluorescence microscopy indicated that the vessels...

... greater in SHR compared to WKY vessels. Using either phentolamine or 6-hydroxydopamine-treated vessels to eliminate a neurogenic adrenergic response, we determined that a part of the HiK-induced contraction was due to NE released from nerve varicosities (i.e., the adrenergic component). In order...

... cells and noradrenergic nerve terminals in the vessel wall. To investigate the presence of presynaptic α-receptors the competitive blocking agent phentolamine was included in the superfusion medium at concentrations ranging from 1 to 50 µM during electrical field stimulation at frequencies between 1...

...Ove A. Nedergaard; Jørgen Schrold Atropine, homatropine, scopolamine, procaine, lidocaine and phentolamine inhibited the contractile response of rabbit isolated pulmonary artery elicited by electrical-field stimulation. Methylatropine had no effect. The inhibition induced by atropine (2 × 10 –6 –2...

... effects were irreversible. In contrast, phentolamine caused a reversible equilibrium block with a rapid onset. Tropolone, which had been subjected to oxygenated physiological salt solution at 37 °C for a prolonged period, accelerated the development of neurogenic block compared to a freshly prepared...

..., instructions or products referred to in the content or advertisements. Vascular reacti Norepinephrine Mesenteric arteries Chickens Phentolamine Hind-limb vessels Acetylcholine Temperature regulation Blood Vessels 11: 212-228 (1974) Development of Vascular Reactivity in Chickens: Responses...

... the actions of 5-HT in a manner which progresses from surmountability to unsurmountability of the blockade depending on the concentration of LSD. The blockade exerted by LSD is reversed by washing. Phentolamine and diphenhydramine competitively antagonize the actions of NE and H, respectively. The potency...