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Keywords: PGC1α
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Journal Articles
Altered PPARγ Coactivator-1 Alpha Expression in Abdominal Aortic Aneurysm: Possible Effects on Mitochondrial Biogenesis
Available to PurchaseMarike Gabrielson, Emina Vorkapic, Maggie Folkesson, Martin Welander, Andreas Matussek, Jan Dimberg, Toste Länne, Josefin Skogberg, Dick Wågsäter
Journal:
Journal of Vascular Research
J Vasc Res (2016) 53 (1-2): 17–26.
Published Online: 25 June 2016
... alterations of the vascular smooth muscle cells (VSMCs) and aortic tissues. PPARγ coactivator-1 alpha (PGC1α) regulates VSMC migration and matrix formation and is a major inducer of mitochondrial biogenesis and function, including oxidative metabolism. Methods: Protein and gene expression of PGC1α and markers...
