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Keywords: Nitric oxide synthase
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Journal Articles
J Vasc Res (2017) 53 (5-6): 330–339.
Published Online: 17 December 2016
.... Therefore, we investigated the effects and mechanisms of nobiletin on rat isolated mesenteric arteries (MAs). Methods: We examined vasodilation induced by nobiletin on rat isolated MA rings with a tension study, the expression and activity of endothelial nitric oxide synthase (eNOS) with Western blotting...
Journal Articles
J Vasc Res (2014) 51 (3): 175–189.
Published Online: 22 May 2014
... of nitric oxide synthase (NOS), and thus could produce NO via this enzymatic pathway, there is significant evidence against this view [ 30,31,32 ]. Nonetheless, diffusible NO from non-mitochondrial sources in endothelial cells and neurons [ 32,33 ], or NO arising from mitochondria via non-NOS pathways [ 34...
Journal Articles
J Vasc Res (2014) 51 (1): 68–79.
Published Online: 11 December 2013
.... Asymmetric dimethylarginine Endothelial cells Fluorescent NO 550 probe Nitric oxide Nitric oxide imaging Nitric oxide synthase Mouse ESCs (mESCs) and human iPSCs were differentiated into ECs and purified by fluorescence-activated cell sorting using the EC markers CD144 (for mESC-derived ECs...
Journal Articles
J Vasc Res (2011) 48 (3): 252–260.
Published Online: 23 November 2010
...Idit F. Schwartz; Ayelet Grupper; Tamara Chernichovski; Avishai Grupper; Oren Hillel; Anat Engel; Doron Schwartz Objectives: Hyperuricemia provokes endothelial dysfunction (ECD). Decreased endothelial nitric oxide synthase (eNOS) activity is an important source of ECD. Cationic amino acid...
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Journal Articles
Journal Articles
J Vasc Res (1994) 31 (3): 131–143.
Published Online: 23 September 2008
...William C. Sessa Nitric oxide (NO) is an important bio-regulatory molecule in the nervous, immune and cardiovascular systems. NO is synthesized from one of the guanidino nitrogens of L-arginine by the enzyme nitric oxide synthase (NOS). To date, several isoforms of NOS have been purified and cloned...
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Journal Articles
Journal Articles
J Vasc Res (2006) 43 (3): 217–228.
Published Online: 17 May 2006
... by morphometry was increased by 20% in LE but not in BN rats. mRNA levels, determined by RT-PCR, were higher in LE than in BN rats for collagen α1(I), collagen α1(III), MMP2 and its inhibitor TIMP1 at 19 days with ACF. Nitric oxide synthase (NOS) mRNA levels were higher in LE rats at 4 days for the inducible...
Journal Articles
J Vasc Res (2005) 43 (1): 109–119.
Published Online: 21 December 2005
..., whereas relaxation to sodium nitroprusside was similar in both groups. N-nitro- L -arginine (NNLA, a nitric oxide synthase inhibitor), partially inhibited acetylcholine relaxation of vessels from sham mice but not from AngII mice. The residual endothelium-dependent hyperpolarizing-factor-like relaxation...
Journal Articles
J Vasc Res (2005) 42 (1): 55–66.
Published Online: 28 January 2005
... microcirculation. To gain insight into the insulin’s mechanism of action, the effects of its higher concentration (0.18 µ M ) were investigated after inhibition of tyrosine kinase (TK), nitric oxide synthase (NOS), protein kinase C (PKC), phosphatidylinositol 3-kinase and K + (ATP) channels, alone...
Journal Articles
Journal Articles
J Vasc Res (2001) 38 (5): 444–452.
Published Online: 17 September 2001
... to microcirculatory dysfunction and cardiac insufficiency. Two important pathways involved in regulating vasomotor response and barrier function are the activation of nitric oxide synthase (NOS) and upregulation of protein kinase C (PKC). To date, studies of these two signaling proteins have relied mainly...
Journal Articles