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Keywords: Neovascularisation
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Journal Articles
Altered PPARγ Coactivator-1 Alpha Expression in Abdominal Aortic Aneurysm: Possible Effects on Mitochondrial Biogenesis
Available to PurchaseMarike Gabrielson, Emina Vorkapic, Maggie Folkesson, Martin Welander, Andreas Matussek, Jan Dimberg, Toste Länne, Josefin Skogberg, Dick Wågsäter
Journal:
Journal of Vascular Research
J Vasc Res (2016) 53 (1-2): 17–26.
Published Online: 25 June 2016
... of PGC1α was detected in regions of neovascularisation in the adventitia layer. In contrast, the intima/media layer of AAA vessel exhibited defective mitochondrial biogenesis as indicated by low expression of PPARGC1A , VDAC , ATP synthase and citrate synthase. Conclusion: Our results suggest...