... to inihibit MAO-A within serotoninergic neurones at lower doses than are required for inhibition in other neurones. The usefulness of this compound in the elucidation of the functions of intra- and extraneuronal MAO are discussed. 23 9 2008 Monoamine oxidase Amiflamine Clorgyline l -Deprenyl...

...B.A. Callingham This review seeks to discuss the possible importance of monoamine oxidase (MAO) and semicarbazide-sensitive amine oxidase (SSAO) in terminating the effects of released sympathetic transmitters and in the inactivation of endogenous or administered sympathomimetic amines...

... for superfusion and isometric tension recording; the overflow of endogenous catecholamines or 3 H-norepi-nephrine and its metabolites, respectively, were measured in the superfusate. In other experiments the monoamine oxidase activity or the catechol-O-methyltransferase (COMT) activity of the saphenous vein wall...

...R.J. Head; R.E. Stitzel; I.S. de la Lande; S.M. Johnson When assayed on homogenates of the rabbit ear artery up to 192 h after sympathetic denervation, the activity of monoamine oxidase (MAO) showed a small but significant decrease (maximum 9%). The activity of catechol-O-methyl transferase (COMT...

... 9 2008 Blood Vessels 12: 137-160(1975) Adrenergic Mechanisms in the Rabbit Ear Artery A Review I van S. de la La n d e* Department of Human Physiology and Pharmacology, University of Adelaide, Adelaide Key Words. Rabbit ear artery Vasoconstriction Norepinephrine Uptake . Monoamine oxidase...

...P.B. Williams; P.M. Hudgins In the present study, both of the major enzymes, monoamine oxidase and catechol- o -methyltransferase, involved in the degradation of norepinephrine were examined indirectly in segments of rabbit aorta by exposure of tissues to 14 C-norepinephrine and subsequent...

... was not significantly altered in the ear artery probably due, in part, to a concomitant increase in medial permeablity to the transmitter. Extraneuronal transmitter disposition factors, i.e. extraneuronal uptake, monoamine oxidase, and catechol-O-methyltransferase activity are directly related to the wet weight...