... the metalloproteinases that act in concert with other mediators to elevate the systemic blood pressure and to modulate the development of cardiovascular hypertrophy and fibrosis processes are MMP-2, MMP-7, ADAM-12, and ADAM-17. This review offers insights into the activity, differential expression, mutual regulation...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Arteries Calcium Cytoskeleton Hyperplasia Hypertrophy Integrins Ion...

... hypertrophy develops in response to training, pressure or volume overload. Training usually leads to growth of larger coronary vessels but little growth of capillaries, except in young animals. However, growth of the capillary bed, but not the resistance vasculature capacity, can be induced by either...

...’ one at a time, whilst the others were held constant: only narrowing of ri led to increases in both S and R min ; with hypertrophy alone, S increased but R min was reduced, whilst increased wall stiffness increased R min but lowered S. Thus, for hypertrophy to be associated with rises of both S and R...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 30 10 1991 9 03 1992 23 9 2008 Losartan Captopril Spontaneously hypertensive rats Hypertrophy Hypertension Angiotensin II James J. Morton...

...-oncogenes are important processes in the development of vascular hypertrophy seen in this model of hypertension. Research Paper J Vase Res 1993;30:13-22 David H. Maclverc Nicola K. GreenQ Michael D. Gammagec Helen Durkina Ashley S. Izzarda Jayne A. Franklynb Anthony M. Heagertya Department of Medicine...

... hypertensive rats (SHR) and age-matched Wistar-Kyoto normotensive rats (WKY). Changes were observed only in muscular and arteriolar vessels of SHR, mainly as thickening of the vessel wall due to hypertrophy of the media. In muscular arteries, hypertrophy of the endothelial cells, widening of the subendothelial...

...Michiel W.M. Knaapen; Pamela Somers; Hilde Bortier; Guido R.Y. De Meyer; Mark M. Kockx Varicose veins are characterized by dilated and thickened vein walls. This study examined whether the changes that occur in varicose veins are associated with smooth muscle cell (SMC) hypertrophy, cellular...

... with essential hypertension, did not occur until a little over 100 years ago [ 2 ]. Before this, Richard Bright had noted that pathological changes in the kidney were often associated with left ventricular hypertrophy [ 3 ]and he suggested that changes in the small vessels might require a greater cardiac force...

... effector. In the aorta, the local sympathetic nervous system appears to control protein synthesis. The heterogeneity in downstream effectors should be considered in studies investigating signaling events related to protein synthesis, which is used as an early marker of hypertrophy. 19 6 2003 ©...