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Keywords: Human umbilical vein endothelial cells
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Journal Articles

Protective Effects of 1,25 Dihydroxyvitamin D 3 against High-Glucose-Induced Damage in Human Umbilical Vein Endothelial Cells Involve Activation of Nrf2 Antioxidant Signaling

Subject Area:
Cardiovascular System , Further Areas
Meifang Wu, Ying Wu, Kaizu Xu, Liming Lin
Journal: Journal of Vascular Research
J Vasc Res (2021) 58 (4): 267–276.
https://doi.org/10.1159/000515512
Published Online: 04 May 2021
...Meifang Wu; Ying Wu; Kaizu Xu; Liming Lin Aim: To explore the protective effects and related mech-anisms of 1,25 dihydroxyvitamin D 3 (1,25(OH) 2 D 3 ) on en-dothelial dysfunction under hyperglycemic conditions. Methods: Cultured human umbilical vein endothelial cells (HUVECs) were treated...
View article titled, Protective Effects of 1,25 Dihydroxyvitamin D 3 against High-Glucose-Induced Damage in <span class="search-highlight">Human</span> <span class="search-highlight">Umbilical</span> <span class="search-highlight">Vein</span> <span class="search-highlight">Endothelial</span> <span class="search-highlight">Cells</span> Involve Activation of Nrf2 Antioxidant Signaling
Open the PDF for Protective Effects of 1,25 Dihydroxyvitamin D 3 against High-Glucose-Induced Damage in <span class="search-highlight">Human</span> <span class="search-highlight">Umbilical</span> <span class="search-highlight">Vein</span> <span class="search-highlight">Endothelial</span> <span class="search-highlight">Cells</span> Involve Activation of Nrf2 Antioxidant Signaling in another window
Journal Articles

3,4,5-Trihydroxycinnamic Acid Inhibits LPS-Induced Inflammatory Response by Increasing SIRT1 Expression in Human Umbilical Vein Endothelial Cells

Subject Area:
Cardiovascular System , Further Areas
Jin-Young Park, Hee Jae Lee, Yong-Soo Kwon, Wanjoo Chun
Journal: Journal of Vascular Research
J Vasc Res (2020) 57 (5): 302–310.
https://doi.org/10.1159/000507628
Published Online: 19 June 2020
... endothelial cells has not been clearly examined. The goal of the present study was to elucidate the anti-inflammatory properties of THC and its underlying mechanism in LPS-challenged human umbilical vein endothelial cells (HUVECs). THC significantly suppressed LPS-induced interleukin-1β production...
View article titled, 3,4,5-Trihydroxycinnamic Acid Inhibits LPS-Induced Inflammatory Response by Increasing SIRT1 Expression in <span class="search-highlight">Human</span> <span class="search-highlight">Umbilical</span> <span class="search-highlight">Vein</span> <span class="search-highlight">Endothelial</span> <span class="search-highlight">Cells</span>
Open the PDF for 3,4,5-Trihydroxycinnamic Acid Inhibits LPS-Induced Inflammatory Response by Increasing SIRT1 Expression in <span class="search-highlight">Human</span> <span class="search-highlight">Umbilical</span> <span class="search-highlight">Vein</span> <span class="search-highlight">Endothelial</span> <span class="search-highlight">Cells</span> in another window
Journal Articles

Comparative Anti-Platelet Profiling Reveals a Potent Anti-Aggregatory Effect of CD34+ Progenitor Cell-Derived Late-Outgrowth Endothelial Cells in vitro

Subject Area:
Cardiovascular System , Further Areas
Vasileios G. Chantzichristos, Fani Gkrozou, Konstantinos Stellos, Minas E. Paschopoulos, Alexandros D. Tselepis
Journal: Journal of Vascular Research
J Vasc Res (2018) 55 (1): 13–25.
https://doi.org/10.1159/000481779
Published Online: 02 December 2017
... (NO) and prostacyclin (PGI 2 ) that were secreted from EOCs, OECs, and human umbilical vein endothelial cells (HUVECs) were also assessed. Results: Among all progenitors, OECs and their supernatant exhibited the most potent inhibitory activity towards platelet aggregation. Furthermore, OECs and their supernatant...
View article titled, Comparative Anti-Platelet Profiling Reveals a Potent Anti-Aggregatory Effect of CD34+ Progenitor Cell-Derived Late-Outgrowth Endothelial Cells in vitro
Open the PDF for Comparative Anti-Platelet Profiling Reveals a Potent Anti-Aggregatory Effect of CD34+ Progenitor Cell-Derived Late-Outgrowth Endothelial Cells in vitro in another window
Journal Articles

Effect of Calcium-Infiltrated Hydroxyapatite Scaffolds on the Hematopoietic Fate of Human Umbilical Vein Endothelial Cells

Subject Area:
Cardiovascular System , Further Areas
Qinghao Zhang, Jörg C. Gerlach, Eva Schmelzer, Ian Nettleship
Journal: Journal of Vascular Research
J Vasc Res (2017) 54 (6): 376–385.
https://doi.org/10.1159/000481778
Published Online: 23 November 2017
... supporting the maintenance of the hematopoietic stem cells niche. We fabricated hydroxyapatite scaffolds with high surface calcium concentration by infiltration, and used human umbilical vein endothelial cells (HUVECs) as a model to study the effects on hematopoietic lineage direction. HUVECs are umbilical...
View article titled, Effect of Calcium-Infiltrated Hydroxyapatite Scaffolds on the Hematopoietic Fate of <span class="search-highlight">Human</span> <span class="search-highlight">Umbilical</span> <span class="search-highlight">Vein</span> <span class="search-highlight">Endothelial</span> <span class="search-highlight">Cells</span>
Open the PDF for Effect of Calcium-Infiltrated Hydroxyapatite Scaffolds on the Hematopoietic Fate of <span class="search-highlight">Human</span> <span class="search-highlight">Umbilical</span> <span class="search-highlight">Vein</span> <span class="search-highlight">Endothelial</span> <span class="search-highlight">Cells</span> in another window
Journal Articles

Epigallocatechin-3-Gallate Ameliorates Angiotensin II-Induced Oxidative Stress and Apoptosis in Human Umbilical Vein Endothelial Cells through the Activation of Nrf2/Caspase-3 Signaling

Subject Area:
Cardiovascular System , Further Areas
Xiuli Zhou, Liwen Liang, Yan Zhao, Hong Zhang
Journal: Journal of Vascular Research
J Vasc Res (2017) 54 (5): 299–308.
https://doi.org/10.1159/000479873
Published Online: 23 September 2017
...Xiuli Zhou; Liwen Liang; Yan Zhao; Hong Zhang Introduction: This study aimed to investigate whether epigallocatechin-3-gallate (EGCG) shows antioxidant activity against angiotensin II (Ang II)-induced human umbilical vein endothelial cell (HUVEC) apoptosis. Materials and Methods: The viability...
View article titled, Epigallocatechin-3-Gallate Ameliorates Angiotensin II-Induced Oxidative Stress and Apoptosis in <span class="search-highlight">Human</span> <span class="search-highlight">Umbilical</span> <span class="search-highlight">Vein</span> <span class="search-highlight">Endothelial</span> <span class="search-highlight">Cells</span> through the Activation of Nrf2&#x2F;Caspase-3 Signaling
Open the PDF for Epigallocatechin-3-Gallate Ameliorates Angiotensin II-Induced Oxidative Stress and Apoptosis in <span class="search-highlight">Human</span> <span class="search-highlight">Umbilical</span> <span class="search-highlight">Vein</span> <span class="search-highlight">Endothelial</span> <span class="search-highlight">Cells</span> through the Activation of Nrf2/Caspase-3 Signaling in another window
Journal Articles

Rapamycin Promotes the Autophagic Degradation of Oxidized Low-Density Lipoprotein in Human Umbilical Vein Endothelial Cells

Subject Area:
Topic Article Package: Pharmacology 2016 , Cardiovascular System , Further Areas
Yanlin Zhang, Qiao Han, Shoujiang You, Yongjun Cao, Xia Zhang, Huihui Liu, Lifang Hu, Chun-Feng Liu
Journal: Journal of Vascular Research
J Vasc Res (2016) 52 (3): 210–219.
https://doi.org/10.1159/000441143
Published Online: 02 December 2015
... in human umbilical vein endothelial cells (HUVECs). Because of this, subsequent studies were designed to elucidate the possible role of the autophagic inducer, rapamycin, on ox-LDL degradation in endothelial cells. Methods: Intracellular cholesterol content was measured using a tissue total cholesterol...
View article titled, Rapamycin Promotes the Autophagic Degradation of Oxidized Low-Density Lipoprotein in <span class="search-highlight">Human</span> <span class="search-highlight">Umbilical</span> <span class="search-highlight">Vein</span> <span class="search-highlight">Endothelial</span> <span class="search-highlight">Cells</span>
Open the PDF for Rapamycin Promotes the Autophagic Degradation of Oxidized Low-Density Lipoprotein in <span class="search-highlight">Human</span> <span class="search-highlight">Umbilical</span> <span class="search-highlight">Vein</span> <span class="search-highlight">Endothelial</span> <span class="search-highlight">Cells</span> in another window
Journal Articles

Inhibition of Protein Kinase C β 2 Prevents Tumor Necrosis Factor-α-Induced Apoptosis and Oxidative Stress in Endothelial Cells: The Role of NADPH Oxidase Subunits

Subject Area:
Cardiovascular System , Further Areas
Bingqing Deng, Shuanglun Xie, Jingfeng Wang, Zhengyuan Xia, Ruqiong Nie
Journal: Journal of Vascular Research
J Vasc Res (2012) 49 (2): 144–159.
https://doi.org/10.1159/000332337
Published Online: 18 January 2012
...Bingqing Deng; Shuanglun Xie; Jingfeng Wang; Zhengyuan Xia; Ruqiong Nie We investigate the cell signal transduction pathway protein kinase C (PKC) and the role of NADPH subunits in the process of TNF-α-induced endothelial apoptosis. Human umbilical vein endothelial cells (HUVEC) were treated...
View article titled, Inhibition of Protein Kinase C β 2 Prevents Tumor Necrosis Factor-α-Induced Apoptosis and Oxidative Stress in Endothelial Cells: The Role of NADPH Oxidase Subunits
Open the PDF for Inhibition of Protein Kinase C β 2 Prevents Tumor Necrosis Factor-α-Induced Apoptosis and Oxidative Stress in Endothelial Cells: The Role of NADPH Oxidase Subunits in another window
Journal Articles

C-Reactive Protein-Induced Endothelial Microparticle Generation in HUVECs Is Related to BH 4 -Dependent NO Formation

Subject Area:
Cardiovascular System , Further Areas
Jie-Mei Wang, Yan Wang, Jun-Yi Huang, Zhen Yang, Long Chen, Li-Chun Wang, An-Li Tang, Zhou-Fen Lou, Jun Tao
Journal: Journal of Vascular Research
J Vasc Res (2007) 44 (3): 241–248.
https://doi.org/10.1159/000100558
Published Online: 09 March 2007
... of endothelial injury. Methods: In vitro cultured human umbilical vein endothelial cells (HUVECs) were incubated with CRP (20 mg/l) for 24 h. The numbers of EMPs with CD31- and CD51-positive staining were assessed flow-cytometrically, and NO production was measured using the Griess reaction in the presence...
View article titled, C-Reactive Protein-Induced Endothelial Microparticle Generation in HUVECs Is Related to BH 4 -Dependent NO Formation
Open the PDF for C-Reactive Protein-Induced Endothelial Microparticle Generation in HUVECs Is Related to BH 4 -Dependent NO Formation in another window