... was prepared by electrospinning and surface modification with heparin via hexamethylenediamine. Then the scaffolds were implanted into the infrarenal abdominal aorta of Wistar rats and contrast-enhanced micro-ultrasound was used to monitor the patency of grafts after implantation. These grafts were extracted...

...Seitaro Mutoh; Monika M. Clowes; Alexander W. Clowes The effect of heparin on the amount of membrane-associated heparan sulfate proteoglycan (HSPG) was examined biochemically in balloon-injured rat carotid arteries. Heparin (Choay 1772) was administered at the rate of 1 mg/kg/h i.v. by an osmotic...

...P.A. Underwood; S.M. Mitchell; J.M. Whitelock The proliferation of vascular smooth muscle cells (VSMC) plays a significant part in both the developing atherosclerotic lesion and in restenosis. Heparin has been widely reported to inhibit the growth of VSMC in culture and intimal VSMC in some animal...

...Cristy S. Dougherty; Linda J. Lowe-Krentz Heparin is a natural anticoagulant molecule that can alter the activity and/or levels of other molecules involved in blood coagulation. Protein S, an anticoagulant protein, is synthesized and released into the plasma by endothelial cells. Immunological...

... sulfate Chondroitin-4-sulfate Chondroitin-6-sulfate Dermatan sulfate Heparin 35 S-incorporation Aortic cholesterol Blood Vessels 16: 177-185 (1979) ¿-Ascorbic Acid: Effects on Aortic Glycosaminoglycan 35S Incorporation in Rabbit-Induced Atherogenesis Anthony J . Verlangieri and J e f f W...

... the activity causing hydrolysis of triglycerides with short-chain fatty acids and monoacylesters decreases up to 60% by analogous treatment. No changes in the hydrolytic activity occurs in presence of sodium heparin. This indicates that this activity is not identical with a lipoprotein lipase. 23 09 1974...

...Eric Durand; Dominique Helley; Ayman Al Haj Zen; Céline Dujols; Patrick Bruneval; Sylvia Colliec-Jouault; Anne-Marie Fischer; Antoine Lafont Background: Therapeutic use of unfractionated heparin and low molecular weight heparins (LMWHs) is limited by hemorrhagic adverse effects. We compared...

...Kazue Kuwahara-Watanabe; Chiaki Hidai; Hiromi Ikeda; Yoshikazu Aoka; Ken-ichiro Ichikawa; Nobuo Iguchi; Masako Okada-Ohno; Jinko Yokota; Hiroshi Kasanuki; Masatoshi Kawana Heparin, which is widely used as an anticoagulant, has been shown to have antiatherosclerotic and antihypertensive effects...