.... The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Visual Abstract Cerebral blood flow Endothelium Resistance arteries Endothelin-1...

...Yen Lin Chen; Thomas M. Baker; Frank Lee; Bo Shui; Jane C. Lee; Petr Tvrdik; Michael I. Kotlikoff; Swapnil K. Sonkusare Introduction: Studies in Cx40-GCaMP2 mice, which express calcium biosensor GCaMP2 in the endothelium under connexin 40 promoter, have identified the unique properties...

... in responding to various extracellular stimuli. In this review, we examine protein localization in the endothelium of resistance arteries, with occasional references to other vessels for contrast, and how that polarization contributes to endothelial function and ultimately whole organism physiology. We...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Visual Abstract Visual Abstract. Sepsis Endothelium Vascular...

... at the anastomosis site, frequent needle puncture, or foreign body reaction to the graft, as well as endothelial dysfunction induced by uremia, are predisposing factors for the development of NH. The injured endothelium secretes various profibrotic cytokines and growth factors, such as platelet-derived growth factor...

... well-organized neotissue with endothelium formation, smooth muscle regeneration, and extracellular matrix formation. Such findings confirm feasibility to create heparin-conjugated scaffolds of next-generation vascular grafts. zhangjiandoctor@126.com 19 08 2018 15 10 2018 28 11...

...-AMPK) were given a high fat diet to induce obesity or kept on standard chow as lean controls for up to 2 years. A subset of obese animals was changed to standard chow after 30 weeks of high fat feeding. En-dothelium-dependent and endothelium-independent responses were examined by isometric tension...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2018 RANKL Osteoprotegerin Calcification Cyclic strain Endothelium Smooth muscle Vascular calcification (VC...

...-univ.hu 3 11 2017 29 12 2017 14 2 2018 Coronary arterioles Daily exercise Elasticity Contractility Endothelium Vascular Remodeling Coronary arterioles were allowed to equilibrate for 1 h in Krebs solution at 60 mm Hg intraluminal pressure, during which all arterioles...

.... The endothelium transduces chemical and mechanical signals into changes in the cytoplasmic calcium concentration to control vascular function. However, studying endothelial calcium signaling in larger arteries in a physiological configuration is challenging because of the requirement to focus through the artery...

... were studied. Functional responses to noradrenaline (NA), potassium chloride and endothelium-dependent and independent relaxations were investigated in vitro using acetylcholine hydrochloride (ACh) and sodium nitroprusside (SNP), respectively. Effects of the nitric oxide synthase (NOS) substrate L...

...% NaCl) diet. Angiotensin-(1-7) and AVE0991 elicited relaxation, and angiotensin-(1-7) unmasked vasodilator responses to bradykinin in arteries from HS-fed rats. These effects of angiotensin-(1-7) and AVE0991 were inhibited by endothelium removal, A779, PD123319, HOE140 and L -NAME. Angiotensin-(1-7...

... inflammatory aneurysm, whereas intraluminal elastase perfusion shows chronic inflammation with angiogenesis and endothelial destruction, thus better mimicking human disease. Abdominal aortic aneurysms Aneurysm mouse model Angiogenesis Elastase infusion Endothelium Inflammation Abdominal aortic...

... (NO), inflammation and endothelium to obesity-induced PVAT damage. Methods: Rats were fed a high-fat diet or normal chow. PVAT function was assessed using wire myography. Skeletonised and PVAT-intact mesenteric vessels were prepared with and without endothelium. Vessels were incubated with L -NNA or superoxide...

..., ascending vasodilation (AVD) increases blood flow into the microcirculation. Once initiated, e.g. through local activation of K + channels in endothelial cells (ECs), hyperpolarization is conducted through gap junctions along the endothelium. Via EC projections through the internal elastic lamina...

.... Endothelium Glucagon-like peptide-1 Restenosis Smooth muscle cells Ultrasound Type-2 diabetes and insulin resistance are intimately associated with atherosclerosis of the large vessels (macroangiopathy), which is the major cause of morbidity and mortality in these patients, and is often preceded...

.... In contrast, saffron increased this response in rubbed segments from SHR but not Wistar rats. Conclusion: Crocetin exerts healthy vasomodulatory effects in hypertension, strongly improving endothelium-dependent ACH relaxations via endothelial nitric oxide but not the cyclooxygenase pathway. This work proposes...

...Ángel Luis García-Villalón; Miriam Granado; Luis Monge; Nuria Fernández; Gonzalo Carreño-Tarragona; Sara Amor To determine the involvement of purinergic receptors in coronary endothelium-dependent relaxation, the response to acetylcholine (1 × 10 -8 to 3 × 10 -7 M ) was recorded in isolated rat...

...Ayaz M. Rahman; Jonathan R. Murrow; Muhiddin A. Ozkor; Nino Kavtaradze; Ji Lin; Christine De Staercke; W. Craig Hooper; Amita Manatunga; Salim Hayek; Arshed A. Quyyumi Aims: Bradykinin (BK) stimulates tissue plasminogen activator (t-PA) release from human endothelium. Although BK stimulates both...

...)-dependent potassium channels on the inner mitochondrial membrane (mitoK ATP channels) is a specific and dependable way to induce protection of neurons, astroglia, and cerebral vascular endothelium. Through the opening of mitoK ATP channels, mitochondrial depolarization leads to activation of protein kinases...