... for superfusion and isometric tension recording; the overflow of endogenous catecholamines or 3 H-norepi-nephrine and its metabolites, respectively, were measured in the superfusate. In other experiments the monoamine oxidase activity or the catechol-O-methyltransferase (COMT) activity of the saphenous vein wall...

...Trajko Trajkov; Barry A. Berkowitz; Sydney Spector Catechol-O-methyltransferase (COMT) activity was measured in the aorta and mesenteric arteries of hypertensive rats. In both spontaneously hypertensive rats (SHR) and uninephrectomized-DOCA salt treated hypertensive rats COMT activity per milligram...

...P.B. Williams; P.M. Hudgins In the present study, both of the major enzymes, monoamine oxidase and catechol- o -methyltransferase, involved in the degradation of norepinephrine were examined indirectly in segments of rabbit aorta by exposure of tissues to 14 C-norepinephrine and subsequent...

... was not significantly altered in the ear artery probably due, in part, to a concomitant increase in medial permeablity to the transmitter. Extraneuronal transmitter disposition factors, i.e. extraneuronal uptake, monoamine oxidase, and catechol-O-methyltransferase activity are directly related to the wet weight...