...Yen Lin Chen; Thomas M. Baker; Frank Lee; Bo Shui; Jane C. Lee; Petr Tvrdik; Michael I. Kotlikoff; Swapnil K. Sonkusare Introduction: Studies in Cx40-GCaMP2 mice, which express calcium biosensor GCaMP2 in the endothelium under connexin 40 promoter, have identified the unique properties...

... (LP) event in preparation for controlling hemorrhage during parturition. We also hypothesized that gestational increases in RhoA-induced vascular smooth muscle (VSM) calcium sensitivity are contributory and occur under the tonic influence of nitric oxide (NO). Second-order pre-placental radial...

...Qinghao Zhang; Jörg C. Gerlach; Eva Schmelzer; Ian Nettleship Foamed hydroxyapatite offers a three-dimensional scaffold for the development of bone constructs, mimicking perfectly the in vivo bone structure. In vivo, calcium release at the surface is assumed to provide a locally increased gradient...

... or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Calcium Calcium spikes Estrogen...

... TRPC3 Endothelium Smooth muscle Vascular Calcium Vasorelaxation Vasoconstriction Knockout mouse National Institutes of Health (NIH) 10.13039/100000002 The canonical transient receptor potential (TRPC) channels comprise a family of nonselective cation channels (TRPC1–7...

...Anneloes Martinsen; Xavier Yerna; Géraldine Rath; Elvira Leon Gomez; Chantal Dessy; Nicole Morel In addition to its role in the regulation of artery contraction, Rho kinase (ROCK) was reported to be involved in the cytosolic calcium response to vasoconstrictor agonists in rat aorta and superior...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Shear stress Intraluminal flow Blood vessels Flow-contraction Sodium Calcium...

...A.D. Hughes Control of intracellular Ca 2+ ([Ca 2+ ] i ) is critical to vascular smooth muscle function. Calcium channels are the major route by which Ca 2+ enters the smooth muscle cell. This article reviews the types of calcium channel present in vascular smooth muscle cells...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Arteries Calcium Cytoskeleton Hyperplasia Hypertrophy Integrins Ion...

...Gabriel Helmlinger; Bradford C. Berk; Robert M. Nerem The influence of flow-imposed shear stress on the intracellular calcium concentration ([Ca 2+ ]i) of cultured endothelial cells (ECs) remains incompletely understood. In the present study, we measured [Ca 2+ ]i in single bovine aortic ECs, using...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Calcium Vascular smooth muscle Serotonin Digital imaging Fluorescence microscopy Blood Vessels 1991;28:252-261 Spatial and Temporal...

...Robert R. Ruffolo, Jr.; Andrew J. Nichols; Mabayoje A. Oriowo In the rat vasculature, a single α 1 -adrenoceptor may be coupled to two distinct G proteins, one of which regulates phospholipase C activity and is insensitive to pertussis toxin, and another which regulates calcium channel function...

...-nucleotide-dependent relaxation. 23 9 2008 Cyclic GMP Cyclic AMP Protein kinases Smooth muscle Calcium Relaxation EDRF © 1991 S. Karger AG, Basel 1991 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other...

... metabolism is inhibited. ATP-sensitive K + channels Calcium Cyanide Glibenclamide Electrophysiology Vascular smooth muscle Vascular tone Research Paper J Vase Res 1994;31:82-91 Marie-Louise Lydrup Karl Sward Per Hellstrand Department of Physiology and Biophysics. University of Lund, Sweden...

...Randal O. Dull; John M. Tarbell; Peter F. Davies Intracellular free calcium ([Ca 2+ ] i ) was measured in single cells of a confluent endothelial monolayer subjected to defined flow. Flow medium containing adenosine triphosphate (ATP) was used to study the influence of flow forces upon agonist...

..., instructions or products referred to in the content or advertisements. Mesenteric artery Vascular smooth muscle Calcium Contraction Research Paper J Vase Res 1992;29:450-460 C.Y. Kwan V. Gaspar /. Berezin A.M. Low E.E. Daniel Smooth Muscle Research Program. Division of Physiology and Pharmacology...

...Zhiming Zhu; Martin Tepel; Marcus Neusser; Walter Zidek To evaluate the direct effects of the angiotensin-converting enzyme (ACE) inhibitors, captopril, enalaprilat, enalapril (a prodrug without therapeutically significant ACE inhibitory effect) and ramiprilat, on cellular calcium metabolism...

... of intracellular calcium, and activation of protein kinase C. These latter two events have been shown to mediate the phosphorylation of numerous proteins, but these substrates and the specific pathways mediating their phosphorylation have not been identified in vascular smooth muscle. Angiotensin II (100 n M , 10...

...Miguel Puerro Vicente; Maria Amaya Aleixandre de Artiñano The mechanism by which calcium administration causes hypotension still remains to be explained. In this paper we have studied the alteration of the pressor effect caused by α 1 and α 2 -adrenoceptor stimulation in the pithed rat after...

... the signal transduction pathways responsible for EDRF release from pulmonary artery endothelium. Mastoparan (10-50 µg/ml) elicited an increase in endothelial cell cytosolic free calcium concentration ([Ca 2+ ] i ) and EDRF release in a concentration-dependent manner. Both effects were dependent on Ca 2...