..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2025 Atherosclerosis Natural killer cells Intravascular ultrasound Mass...

...Bo Zhou; Xiang Wang; Yao Wang; Danan Liu Introduction: This study attempted to observe the role of fibronectin type III domain-containing protein 5 (FNDC5) in atherosclerosis development and the underlying mechanism. Methods: After being fed a high-fat diet (HFD), ApoE −/− mice were injected...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Atherosclerosis Computational fluid dynamics Carotid bulb Plaque location Wall shear stress Carotid artery atherosclerotic stenosis occurs when a plaque narrows...

...Jingyu Piao; Yifan Yin; Yaru Zhao; Yi Han; Huixia Zhan; Duosheng Luo; Jiao Guo Objective: Follicle-stimulating hormone (FSH) level changes may be another reason for increasing the risk of cardiovascular disease. In this study, we aimed to investigate the role of FSH in atherosclerosis and its...

...Jessica Davis-Knowlton; Jacqueline E. Turner; Anne Harrington; Lucy Liaw Introduction: We previously identified Notch2 in smooth muscle cells (SMC) in human atherosclerosis and found that signaling via Notch2 suppressed human SMC proliferation. Thus, we tested whether loss of Notch2 in SMC would...

...Florian Simon; Axel Larena-Avellaneda; Sabine Wipper Animal models have significantly advanced our understanding of the mechanisms of atherosclerosis formation and the evaluation of therapeutic options. The current focus of research is on preventive strategies and includes pharmacologic...

...Christine Vayssettes-Courchay; Christophe Ragonnet; Marc Isabelle; Marie-Pierre Bourguignon; Stefano Chimenti Objectives: Atherosclerosis severely damages the arterial wall. The aim of this study was to assess in vivo, for the first time, arterial dynamic properties, reactivity, and stiffness...

... ADAMTS-4 might play in vascular pathology, which has implications for atherosclerosis and vessel wall abnormalities, as well as for the resulting diseases, such as cardiovascular and cerebrovascular disease, aortic aneurysms, and dissections. Major substrates of ADAMTS-4 are proteoglycans expressed...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Vascular calcification can develop in several locations and conditions. Calcification associated with atherosclerosis is in general restricted...

.... Atherosclerosis Cholesterol SREBF2 Fetus Aortas Dyslipidemia Although the evaluation of molecular mechanisms in atherogenesis is complicated by complex cellular and microenvironmental components involved before symptom manifestation, the atherogenic process develops very slowly, thus offering...

... imaging of solvent-cleared organs Intraplaque angiogenesis Atherosclerosis Atherosclerosis is a progressive inflammatory disease that leads to plaque formation at specific sites of the arterial tree [ 1 ]. Formation of atherosclerotic plaques typically starts with the deposition of lipids...

...Jian Zhao; Chaoji Huangfu; Zhihui Chang; Andrew T. Grainger; Zhaoyu Liu; Weibin Shi Purpose: Atherosclerosis in the carotid arteries is a common cause of ischemic stroke. We examined atherogenesis in the left carotid artery with and without interrupted blood flow of C57BL/6 (B6) and C3H-Apoe...

...: 22 mM). Endothelial senescence was investigated by assessing senescence-associated-β-galactosidase (SA-β-gal), p53, and telomere length. Endothelial function and atherosclerosis were examined by nitric oxide-related-products (NOx: NO 2 – and NO 3 – ), O 2 – , endothelial NO synthase (eNOS), NADPH...

... on the expression of MT1-MMP and ICAM-1 in HUVECs. Conclusion: In this in vitro analysis, dronedarone directly increased platelet activation but showed significant direct effects on endothelial cells and indirect effects on platelets on selected markers of atherosclerosis. [email protected] 9 05...

... in the aorta and coronary arteries. Objectives and Methods: We generated a hypertensive (HTN) rabbit model by surgical removal of the left kidney and partial ligation of the right renal artery. After a 16-week cholesterol diet, we compared aortic and coronary atherosclerosis of HTN rabbits with those...

... atherosclerosis (AS) development are not well understood. Thus, this study investigated the relationship between HMGB1 and vascular inflammation in Apoe –/– mice and whether glycyrrhizin (GLY), a small inhibitor of HMGB1, could have atheroprotective effects in AS. Methods: Apoe –/– mice on a high-fat diet were...

... from any ideas, methods, instructions or products referred to in the content or advertisements. Thyroid hormone receptor-α Vascular smooth muscle cells Renin-angiotensin system Cholesterol Atherosclerosis Research Paper J Vasc Res 2018;55:224 234 DOI: 10.1159/000491430 Received: January 11...

... with AAV8-PCSK9 (adeno-associated virus serotype 8/proprotein convertase subtilisin/kexin type 9) virus leading to hypercholesterolemia, increased low-density lipoprotein, and atherosclerosis in mice fed a high-fat diet (HFD). Mice were co-treated with the mitochondria-targeted superoxide dismutase mimetic...

.... This spontaneous model recapitulates aspects of human atherosclerosis, and allows for the development of dissecting abdominal aortic aneurysms (AAAs) when combined with angiotensin II. We characterized apoE -/- rats and hypothesized that, similar to mice, they would develop dissecting AAAs. We created rats...

... for maintaining the correct tissue integrity. In this study, we have investigated the role of β-sarcoglycan within the matrix-binding dystrophin-glycoprotein complex in the development of atherosclerosis. Results: Atherosclerotic plaque development was significantly reduced in ApoE-deficient mice lacking β...