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Keywords: AP-1
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Journal Articles
Heparin Regulates Transcription of Endothelin-1 Gene in Endothelial Cells
Available to PurchaseKazue Kuwahara-Watanabe, Chiaki Hidai, Hiromi Ikeda, Yoshikazu Aoka, Ken-ichiro Ichikawa, Nobuo Iguchi, Masako Okada-Ohno, Jinko Yokota, Hiroshi Kasanuki, Masatoshi Kawana
Journal:
Journal of Vascular Research
J Vasc Res (2005) 42 (3): 183–189.
Published Online: 03 June 2005
... in fetal calf serum. ET-1 mRNA expression was significantly suppressed by heparin in a dose-dependent manner. Promoter analysis revealed that the minimum ET-1 promoter containing only the GATA and AP-1 sequences as positive cis -acting sites in the ET-1 promoter is sufficient for this suppression. Gel...