...Vincenza Gianfredi; Samuele Vannini; Massimo Moretti; Milena Villarini; Nicola Luigi Bragazzi; Alberto Izzotti; Daniele Nucci Background/Aims: Epigenetics refers to modifications in gene activity and expression without alteration at the DNA sequence. Environment and diet could influence gene...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Epigenetics Germinated brown rice γ-Aminobutyric acid Insulin resistance The burden of diabetes is assuming...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Biomarker Inflammation Epigenetics DNA methylation Diet Fiber Vitamin C...

...Flores Naselli; Nigel Junior Belshaw; Carla Gentile; Marco Tutone; Luisa Tesoriere; Maria Antonietta Livrea; Fabio Caradonna Background: Recently, we have shown anti-proliferative and pro-apoptotic effects of indicaxanthin associated with epigenetic modulation of the onco-suppressor p16 INK4a...

... are an informative basis for further studies to elucidate epigenetic mechanisms underlying DMT2. Additionally, our results might provide starting points for the development of biomarkers for prevention and therapy strategies. [email protected] 10 10 2014 17 03 2015 10 6 2015...

... of risk-associated diets convert a healthy cellular transcriptional program into a pathological one. Epigenetics has enriched our view of the genome by showing that DNA-associated regulatory proteins and RNAs, together with chemical modifications of the DNA itself, determine which parts of the DNA chain...

...Karen A. Lillycrop; Graham C. Burdge Epigenetic processes which include DNA methylation, histone modification and miRNAs are integral in determining when and where specific genes are expressed. There is now increasing evidence that the epigenome is susceptible to a variety of environmental cues...

... and human disease, and the role of gene-nutrient interactions in modifying epigenetic processes. One-carbon metabolism also regulates the expression of methyltransferases, in addition to maintaining the AdoMet/AdoHcy ratio. DMNT1 levels are increased in choline-deficient embryos leading to increased...

.... Conclusion: It is clear that the global undernutrition (UN) during pregnancy in rodents alters glucose metabolism in adult offspring. It has been hypothesised that alterations in epigenetic mechanisms may underlie this phenotype. However, removing all methyl donors during pregnancy, which are essential...

...E.C.M. Mariman Epigenetic phenomena are changes in phenotype that are due to resetting of gene expression under the influence of the environment or genetic factors without changing the DNA sequence. Usually this resetting occurs at a certain stage in life and remains fixed thereafter. In humans...