..., instructions or products referred to in the content or advertisements. DNA methylation Transcriptomics Diet Precision nutrition Obesity Chronic diseases miRNA Biomarkers Genes Polymorphisms Obesity is a global epidemic with more than 35% of the world population (2,100 million people...

...-α (TNF-α) promoter and decreased risk of metabolic changes. Methods: Forty normal-weight young women were involved in this cross-sectional study. DNA was isolated from white blood cells, and CpG site methylation in TNF-α was analyzed by Sequenom EpiTyper. The quality of the diet was assessed...

...Gareth Marlow; Dug Yeo Han; Christopher M. Triggs; Lynnette R. Ferguson Background: Diet is known to play a major role in Crohn's disease (CD). It has also been reported that the minor G allele from the rs12212067 polymorphism (T>G) in FOXO3 is associated with milder CD. The aim of this study...

...Shanil Juma; Victorine Imrhan; Parakat Vijayagopal; Chandan Prasad Of all chronic metabolic diseases, cardiovascular disease (CVD) is the leading cause of death worldwide. Most research over the past 100 years show a link between CVD and lifestyle, including diet; thus, public health messages have...

...Caroline Richard; Patrick Couture; Sophie Desroches; Benjamin Nehmé; Sylvie Bourassa; Arnaud Droit; Benoît Lamarche Background/Aims: The objective of this preliminary study was to examine the impact of the Mediterranean diet (MedDiet) on the high-density lipoprotein (HDL) proteome in men...

... Diet Nutrition Lipids Metabolites Mass spectrometry 8 03 2013 12 07 2013 31 8 2013 Fig. 2 Metabolites. Metabolomics aims to screen metabolites in biological samples. Metabolites can be divided into water-soluble, or hydrophilic, compounds (e.g., nucleotides, amino acids...

... clinical and laboratory evaluations and 3-day weighed diet records. Data on dietary intake were categorized as high or low, based on median values. Results: The AA genotype in the FTO gene was positively associated with high fat (>34% energy; OR = 2.17; 95% CI 1.02-4.63) and low fiber intakes (<16 g...

... of different processes such as cell cycling, programmed cell death, cell differentiation, tumor development, metastasis, and sensing of nutrient stress. This review summarizes the evidence regarding the changes in miRNA expression that are caused by diets with a deficiency or augmented intake of nutrients...

... of risk-associated diets convert a healthy cellular transcriptional program into a pathological one. Epigenetics has enriched our view of the genome by showing that DNA-associated regulatory proteins and RNAs, together with chemical modifications of the DNA itself, determine which parts of the DNA chain...

... Cyclooxygenase 2 Diet Gene Genetic variation ω–3 fatty acids Polyunsaturated fatty acids Prostatic neoplasms Single nucleotide polymorphism Minireview J Nutrigenet Nutrigenomics 2009;2:149 158 DOI: 10.1159/000235565 Published online: September 23, 2009 3 Fatty Acids, Genetic Variants in COX-2...

... origin. This promoted major anatomic, physiologic and metabolic adaptations. Encephalization, which requires high-quality diet, characterizes the evolutionary sequence that, through the Homo ergaster/erectus stages, led to our species, Homo sapiens , which originated in Africa about 200,000 years ago...