Serum from 191 nonhuman primates housed outdoors from October 1977 to October 1978 at the California Primate Research Center was assayed for the presence of antibody specific for coccidioidin. One Macaco mulatta had coccidioidal antibody which was found to be associated with disseminated coccidioidomycosis. One Macaco radiata had complement-fixing antibody specific for coccidioidin and a pulmonary lesion. Additionally,two other animals had coccidioidal antibody but lacked clinical evidence of disease. The source of infection is suspected to be a severe dust storm originating in southern California.

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