... in the immune response. The K562 cells cultured in 96-well plates (3 × 10 4 cells per well) were mixed with lymphocytes added at a 20:1 ratio and incubated at 37°C for 3-24 h. The inhibition test was conducted with polyclonal antibodies (anti-NKG2D, anti-MicA, anti-Fas, anti-FasL, and anti-granzyme B...

...Annabelle Chauveau; Pierre Tonnerre; Angélique Pabois; Pierre-Jean Gavlovsky; Mathais Chatelais; Stéphanie Coupel; Béatrice Charreau MICA are major histocompatibility complex class I-related molecules, expressed by endothelial cells (ECs), that may be targets for alloantibodies and NKG2D-expressing...

.... Although the expression of ligands for NK cell-activating receptors is variable, the majority of melanoma cell lines express ligands for NKG2D and for DNAX accessory molecule-1 (DNAM-1). While the NKG2D receptor has been described as the principal entity responsible for the lysis of several melanoma cell...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Immunosurveillance Tumor immune escape Viral immune evasion Natural killer cell therapy Ligand shedding NKG2D Neuroblastoma Natural killer cells Journal of Innate...