...Gunnar Pejler; Sultan Alanazi; Mirjana Grujic; Jeremy Adler; Anna-Karin Olsson; Christian P. Sommerhoff; Fabio Rabelo Melo Previous research has indicated an intimate functional communication between mast cells (MCs) and neutrophils during inflammatory conditions, but the nature...

...Aida Paivandy; Gunnar Pejler Mast cells (MCs) are versatile effector cells of the immune system, characterized by a large content of secretory granules containing a variety of inflammatory mediators. They are implicated in the host protection toward various external insults, but are mostly well...

...Gunnar Pejler Mast cells are now recognized as key players in diverse pathologies, but the mechanisms by which they contribute in such settings are only partially understood. Mast cells are packed with secretory granules, and when they undergo degranulation in response to activation the contents...

...Liliana Portales-Cervantes; Ian D. Haidl; Patrick W. Lee; Jean S. Marshall Mucosal surfaces are protected from infection by both structural and sentinel cells, such as mast cells. The mast cell's role in antiviral responses is poorly understood; however, they selectively recruit natural killer (NK...

...J. Daan de Boer; Jack Yang; Florry E. van den Boogaard; Arie J. Hoogendijk; Regina de Beer; Jaring S. van der Zee; Joris J.T.H. Roelofs; Cornelis van 't Veer; Alex F. de Vos; Tom van der Poll Background: Mast cells are implicated in allergic and innate immune responses in asthma, although...

...Minoru Fukuda; Hiroko Ushio; Junko Kawasaki; Francois Niyonsaba; Mizuho Takeuchi; Tadashi Baba; Keiichi Hiramatsu; Ko Okumura; Hideoki Ogawa To investigate the precise mechanisms of virus recognition by mast cells, the expression and functional characteristics of virus recognition receptors...

...Jens Abel; Oliver Goldmann; Christina Ziegler; Claudia Höltje; Mark S. Smeltzer; Ambrose L. Cheung; Daniela Bruhn; Manfred Rohde; Eva Medina In this study, we investigated the interactions of Staphylococcus aureus with mast cells, which are multifunctional sentinels lining the surfaces of the body...