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Keywords: Macrophage
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Journal Articles
Journal Articles
J Innate Immun (2024) 16 (1): 188–202.
Published Online: 05 March 2024
... evidence suggests a connection between drug resistance and immune dysregulation. Summary: As a ubiquitously distributed, versatile innate immune cell, macrophages play essential roles in maintaining tissue homeostasis in a steady state. Nevertheless, it is becoming aware that macrophages undermine...
Journal Articles
J Innate Immun (2024) 16 (1): 143–158.
Published Online: 03 February 2024
...Ying-Tsun Chen; Gaurav Kumar Lohia; Samantha Chen; Sebastián A. Riquelme Background: Upon infection, mucosal tissues activate a brisk inflammatory response to clear the pathogen, i.e., resistance to disease. Resistance to disease is orchestrated by tissue-resident macrophages, which undergo...
Journal Articles
J Innate Immun (2024) 16 (1): 12–30.
Published Online: 28 November 2023
... to in the content or advertisements. 2023 Staphylococcus aureus Biofilm Immunometabolism Macrophage Myeloid-derived suppressor cell Neutrophil NIH Staphylococcus aureus ( S. aureus ) is a common human commensal and significant opportunistic pathogen. Approximately 30% of humans...
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J Innate Immun (2022) 14 (1): 51–68.
Published Online: 09 July 2021
...Ourania Kolliniati; Eleftheria Ieronymaki; Eleni Vergadi; Christos Tsatsanis Macrophages, the central mediators of innate immune responses, being in the first-line of defense, they have to readily respond to pathogenic or tissue damage signals to initiate the inflammatory cascade. Such rapid...
Journal Articles
Journal Articles
J Innate Immun (2021) 13 (6): 391–403.
Published Online: 21 May 2021
... clearance, we hypothesized that HIF-1α could play an important role in coordinating host responses to GBS in colonization and systemic disease. Counter to our hypothesis, we found that GBS infection did not induce HIF-1α expression in vaginal epithelial cells or murine macrophages, nor did HIF-1α deficiency...
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J Innate Immun (2021) 13 (1): 49–59.
Published Online: 09 September 2020
...Tim Bleul; Xinyu Zhuang; Antonia Hildebrand; Clemens Lange; Daniel Böhringer; Günther Schlunck; Thomas Reinhard; Thabo Lapp Purpose: To investigate immunological differences and the role of CD38+/F4/80 + M1 macrophages in C57BL/6J- and BALB/c-recipient mouse corneal transplantation models. Methods...
Journal Articles
J Innate Immun (2019) 11 (3): 280–288.
Published Online: 22 October 2018
... actively suppress proinflammatory immune responses, as evident by the recruitment of myeloid-derived suppressor cells and macrophage (MФ) polarization towards an anti-inflammatory state. Recent studies have shown that alterations in leukocyte metabolism shape their inflammatory phenotype and function...
Journal Articles
J Innate Immun (2019) 11 (3): 289–299.
Published Online: 24 July 2018
... to close contact with infected/carrier individuals. It is an intracellular pathogen, which can survive and replicate in various cells including macrophages, dendritic cells, epithelial cells, and other white blood cells. Once Salmonella crosses the intestinal barrier, it disseminates to various systemic...
Journal Articles
J Innate Immun (2018) 10 (4): 291–305.
Published Online: 03 July 2018
..., instructions or products referred to in the content or advertisements. Bacteria Phosphatidylethanolamine Inflammation Macrophage Dendritic cell National Institutes of Health (NIH) 10.13039/100000002 JournImal omf Inunnaittey Research Article J Innate Immun 2018;10:291 305 DOI: 10.1159...