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Keywords: Innate immunity
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Journal Articles
J Innate Immun (2024) 16 (1): 385–396.
Published Online: 18 July 2024
... reduce patients’ life quality. Summary: AD has complex pathogenesis, including genetic disorders, epidermal barrier dysfunction, abnormal immune responses, microbial dysbiosis of the skin, and environmental factors. Recently, the role of innate immune cells in AD has attracted considerable attention...
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J Innate Immun (2024) 16 (1): 96–104.
Published Online: 19 January 2024
...Carolina Rego Rodrigues; Yadu Balachandran; Gurpreet Kaur Aulakh; Baljit Singh Background: Toll-like receptors (TLRs) are one of the first pattern recognition receptors found in the innate immune system. The TLR family has 12 members (TLR1–TLR9, TLR11–TLR13) in mice and 10 members (TLR1–TLR10...
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J Innate Immun (2021) 13 (6): 391–403.
Published Online: 21 May 2021
... of transcription factor hypoxia-inducible factor 1 alpha (HIF-1α), widely recognized as a regulator of immune activation during infection, in the host response to GBS. Given the importance of endogenous HIF-1α for innate immune defense, and the potential utility of HIF-1α stabilization in promoting bacterial...
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J Innate Immun (2021) 13 (6): 376–390.
Published Online: 17 May 2021
... to in the content or advertisements. Effector mechanisms of insect innate immune systems comprise both soluble and cellular reactions [ 15, 16 ]. Soluble mediators are released from immune-competent organs, primarily the fat body but also the gut, the tracheae, and the salivary glands [ 15, 17-19 ]. Among...
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J Innate Immun (2020) 12 (6): 437–447.
Published Online: 19 June 2020
...Wenxin Wu; Jordan P. Metcalf The important role of interferons (IFNs) in antiviral innate immune defense is well established. Although recombinant IFN-α was approved for cancer and chronic viral infection treatment by regulatory agencies in many countries starting in 1986, no IFNs are approved...
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J Innate Immun (2020) 12 (4): 333–343.
Published Online: 05 December 2019
..., instructions or products referred to in the content or advertisements. Siglec Interleukin-1β Caspase-1 Inflammasome Macrophages Innate immunity Vimentin National Institutes of Health (NIH) 10.13039/100000002 Pathogenic and beneficial microbes establish intimate interactions...
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J Innate Immun (2019) 11 (3): 263–279.
Published Online: 14 November 2018
... aeruginosa to sense bacterial population density and fitness, and regulate virulence, biofilm development, metabolite acquisition, and mammalian host defense. We also focus on the role of N -acylhomoserine lactone-dependent QS signaling in the modulation of innate immune responses connected together via...