... was conducted. The impact of eosinophils on the Th2 response was investigated through experiments involving dblGATA mice, which lack eosinophils and, consequently, eosinophil-derived IL-4. Results: The absence of eosinophils notably influenced Th2 polarization, leading to impaired production of type 2 cytokines...

... in their hosts. This immunomodulation was previously shown to improve diet-induced insulin resistance which is linked to chronic inflammation. In the current study, we demonstrate that infection with the filarial nematode Litomosoides sigmodontis increased the eosinophil number and alternatively activated...

... on a C57BL/6 background were repetitively exposed to HDM via the airways. Results: HDM challenge resulted in a rise in tryptase activity in bronchoalveolar lavage fluid (BALF) of Wt mice, indicative of mast cell activation. Kit w-sh mice showed a strongly attenuated HDM- induced recruitment of eosinophils...

...Marianne Johnsson; Mogens Bove; Henrik Bergquist; Mikael Olsson; Sven Fornwall; Karin Hassel; Agnes E. Wold; Christine Wennerås Blood eosinophil numbers may be elevated in allergy, inflammatory bowel disease and eosinophilic esophagitis. The aim of this study was to examine whether circulating...

...Marcus Svensson-Frej Infiltration of eosinophils into the intestinal mucosa is a typical hallmark of antiparasite immune responses and inflammatory disorders of the intestinal tract, and eosinophils are thought to contribute to these processes by release of their cytotoxic granule content. However...

...Praveen Akuthota; Jason J. Xenakis; Peter F. Weller Eosinophils have long been noted to be present in asthma and other forms of pulmonary inflammation, but whether they act as true offenders or merely as bystanders has been a point of uncertainty. However, in recent years, there has been increasing...