... neutrophils showed TLR10 translocation in the leading edge and TLR10 knockdown in neutrophils reduced their fMLP-induced chemotaxis and the number of neutrophils with pseudopodia but without affecting the expression of key proteins of actin nucleation process, ARP-3 and Diap1. Taken together, our findings...

... species (ROS) and cytokine production); and (2) affect neutrophil chemotaxis in vitro to the penta-peptide, WKYMVm, the chemokine, KC, and leukotriene B 4 . HdE was not cytotoxic to neutrophils, elicited a Ca 2+ response and ROS, but not, cytokine (KC, interleukin-10, tumour necrosis factor-α) generation...

... healing Chemotaxis Host defense The basement membrane (BM) of epithelial tissues is a specialized extracellular matrix (ECM) which separates the epidermis from the dermis. Classically, the BM provides mechanical and structural support for epithelial cells and can directly interact with cells via...

... 7 receptor deficiency dampened subsequent inflammation. This suggests a partnership between two of the main DAMPs that are implicated in neutrophil recruitment, ATP and mitochondria. Inflammation Sterile injury Damage-associated molecular patterns Chemotaxis Neutrophils...

... be dialyzed using a 3.5-kDa pore size membrane. Thus, mouse intestinal lumen contains small, potent and highly efficacious leukocyte chemotactic and activating factors that may be distinct from neutrophils and peripheral blood mononuclear cells and distinct from Fpr1 agonists. Microbiome Chemotaxis...

... baseline PMN migration as well as formyl-methionyl-leucyl-phenylalanine- and IL-8-induced PMN chemotaxis. This inhibitory effect was mediated by the RAGE receptor. In contrast, a higher HMGB1 concentration (5,000 ng/ml) had a chemoattractant effect on PMN through IL-8 production. This effect required...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Inflammation Formylpeptide G protein-coupled receptor Chemotaxis...

... enhanced chemotaxis. These data demonstrate that pathophysiological concentrations of TNF-α elicit NADPH oxidase-derived ROS and prime cells for enhanced surface protein expression, activation of p38 and ERK1/2 MAPK pathways, and increased chemotaxis. Furthermore, PLB-D cells undergo TNF-α priming...

.... stercoralis would trigger eosinophil chemotaxis, and to then compare the chemotactic migration response, including second messenger signals and receptors, to those mechanisms triggered by host chemoattractants. Eosinophils undergo both chemotaxis and chemokinesis to soluble parasite extract in transwell...