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Keywords: Chemokines
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Journal Articles
Journal Articles
J Innate Immun (2018) 10 (5-6): 465–478.
Published Online: 30 August 2018
...Sergio M. Pontejo; Philip M. Murphy; James E. Pease Viruses use diverse molecular mechanisms to exploit and evade the immune response. Herpesviruses, in particular, encode functional chemokine and chemokine receptor homologs pirated from the host, as well as secreted chemokine-binding proteins...
Journal Articles
J Innate Immun (2018) 10 (3): 228–238.
Published Online: 23 May 2018
... investigated. We examined the influence of modulating HO-1 expression on the inflammatory response of human IECs. Engineered deficiency of HO-1 in Caco-2 and T84 IECs led to increased proinflammatory chemokine expression in response to pathogenic bacteria and inflammatory cytokine stimulation. Crosstalk...
Journal Articles
J Innate Immun (2018) 10 (5-6): 479–486.
Published Online: 18 April 2018
... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Atherosclerosis Chemokines Inflammation Monocytes The immune system consists of different specialized leukocytes to protect the organism against pathogens. Beside pathogens...
Journal Articles
J Innate Immun (2016) 8 (5): 493–506.
Published Online: 29 June 2016
... to healthy controls. MDSCs were functionally competent, as they suppressed polyclonal T-cell proliferation, as well as Th1 and Th17 responses. In addition, MDSCs decreased monocytic IL-1β secretion. Multiplex assays revealed a distinct pattern of MDSC-inducing cytokines, chemokines, and growth factors...
Journal Articles
J Innate Immun (2013) 5 (4): 304–314.
Published Online: 05 April 2013
... discusses the molecular mechanisms regulating neutrophil mobilization from the bone marrow, with emphasis on the antagonistic roles of the CXCR4 (C-X-C motif receptor 4)/CXCL12 (C-X-C motif ligand 12) and CXCR2/ELR+ (Glu-Leu-Arg) CXC chemokine signaling axes in the bone marrow. A role for the CXCL12/CXCR4...
Journal Articles
J Innate Immun (2012) 4 (5-6): 489–497.
Published Online: 03 May 2012
... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Chemokines Macrophages Pattern recognition receptors National Institutes of Health (NIH) 10.13039/100000002 Chronic...
Journal Articles
J Innate Immun (2012) 4 (5-6): 498–508.
Published Online: 27 April 2012
... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Chemokines Cytokines Macrophages Atherosclerosis Therapy National Institutes...
Journal Articles
J Innate Immun (2012) 4 (5-6): 542–552.
Published Online: 17 April 2012
...-pulsed BMDC to primary mouse tracheal epithelial cells (MTEC) or MLE-15 cells induced chemokine (C-C) motif ligand (CCL) 20 and granulocyte macrophage (GM) colony-stimulating factor (CSF), both of which are important for DC recruitment, survival and differentiation. Importantly, DC do not produce CCL20...
Journal Articles
Journal Articles
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Journal Articles
J Innate Immun (2011) 3 (6): 614–622.
Published Online: 16 June 2011
... in dendritic cells. Apidaecin upregulated T-lymphocyte co-stimulatory molecule CD80 and cytokine/chemokine production in macrophages, but not in monocytes and dendritic cells. Suboptimal stimulatory doses (5–10 µ M ) of apidaecin partially inhibited the lipopolysaccharide (LPS)-induced increase in major...
Journal Articles
Journal Articles
J Innate Immun (2011) 3 (2): 167–179.
Published Online: 05 November 2010
... of naïve mice to German cockroach (GC) feces (frass) was sufficient to induce dendritic cell (DC) recruiting and activating chemokines C-C motif ligand 20, granulocyte macrophage colony-stimulating factor, granulocyte colony-stimulating factor and macrophage inflammatory protein-1α into the airways...
Journal Articles
J Innate Immun (2009) 1 (5): 480–493.
Published Online: 20 June 2009
... similar IκBα mRNA levels and induction of innate immune genes from 6 h to 10 days after LPS injection. In contrast, NF-κB activity, cytokine, chemokine, TLR2 and CD14 transcripts were no longer detected in MyD88-deficient mice. Indeed, the hybridization signal for most of the transcripts measured...