... between bacteria and host, as well as into strategies to prevent and treat P. aeruginosa infections and reduce the rate of antibiotic resistance. [email protected] 16 05 2018 24 09 2018 14 11 2018 © 2018 The Author(s) Published by S. Karger AG, Basel 2018 Open Access...

...Dani A.C. Heesterbeek; Mathieu L. Angelier; Richard A. Harrison; Suzan H.M. Rooijakkers Complement is a complex protein network of plasma, and an integral part of the innate immune system. Complement activation results in the rapid clearance of bacteria by immune cells, and direct bacterial killing...

..., instructions or products referred to in the content or advertisements. Bacteria Phosphatidylethanolamine Inflammation Macrophage Dendritic cell National Institutes of Health (NIH) 10.13039/100000002 JournImal omf Inunnaittey Research Article J Innate Immun 2018;10:291 305 DOI: 10.1159...

..., instructions or products referred to in the content or advertisements. Peptidoglycan recognition protein Anopheles Drosophila Immune-deficiency pathway Antimicrobial peptides Plasmodium Microbiota Bacteria In sub-Saharan Africa, malaria parasites are mainly transmitted by 2 sibling...

... (TAT-PRNK) significantly impaired CR3-mediated phagocytosis without affecting FcγR-mediated uptake. In addition, Pyk2 was strongly recruited to complement opsonized Escherichia coli and the pharmacological inhibition of Pyk2 significantly decreased uptake of the bacteria. Finally, CRISPR/Cas-mediated...

...Mathias Faure; Frank Lafont Innate immunity induces rapid responses to fight invading pathogens. To eliminate intracellular bacteria or viruses, innate cellular responses lead to the production of nuclear factor-κB-dependent inflammatory cytokines, inflammasome activation, type I interferon...

... defense. All bacteria were cultivated to the mid-logarithmic phase (the optical density at 620 nm was 0.4) in broth, washed and diluted (1:1,000) in incubation buffer (10 m M Tris-HCl, containing 5 m M glucose, pH 7.4). Fifty microliters of bacteria [10 6 colony-forming units (CFU)/ml] were...

..., physical and biological properties of these glycoproteins. The hydrolysis of glycoprotein glycans by bacterial glycosidases can have dramatic effects on glycoprotein function and, thereby, be beneficial for the bacteria in different ways. This review gives an introduction to the expanding field...

...Jessica Humann; Laurel L. Lenz Peptidoglycan (PGN) is a major component of the bacterial cell envelope in both Gram-positive and Gram-negative bacteria. These muropeptides can be produced or modified by the activity of bacterial glycolytic and peptidolytic enzymes referred to as PGN hydrolases...