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Keywords: Atherosclerosis
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Journal Articles
J Innate Immun (2018) 10 (5-6): 479–486.
Published Online: 18 April 2018
...Ariane Schumski; Carla Winter; Yvonne Döring; Oliver Soehnlein Atherosclerosis is a chronic inflammation of the arterial vessel wall that arises from an imbalanced lipid metabolism. A growing body of literature describes leukocyte recruitment as a critical step in the initiation and progression...
Journal Articles
J Innate Immun (2013) 5 (4): 358–366.
Published Online: 05 April 2013
...Maik Drechsler; Oliver Soehnlein Accumulation of classical monocytes is imperative for the progression of atherosclerosis. Hence, therapeutic interference with mechanisms of lesional monocyte recruitment, the primary mechanism controlling macrophage accumulation, may allow for targeting...
Journal Articles
Journal Articles
J Innate Immun (2012) 4 (3): 260–272.
Published Online: 22 November 2011
...Lorenza Francescut; Tanja Steiner; Simon Byrne; Katherine Cianflone; Sheila Francis; Cordula Stover Atherosclerosis is a chronic progressive inflammatory disease which manifests in the arterial vascular tree. It is a major cause of cardiovascular morbidity and contributes significantly to mortality...
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Journal Articles
J Innate Immun (2010) 2 (4): 325–333.
Published Online: 07 May 2010
... in atherosclerosis. While one study found that IL-17 is protective against atherosclerosis, several other recent studies have suggested that IL-17 plays a proatherogenic role. Thus, the function of IL-17 remains controversial and awaits more direct studies to address the issue. In this review, we will highlight all...
Journal Articles
J Innate Immun (2010) 2 (4): 307–315.
Published Online: 30 April 2010
... the role of TLR endogenous activators in disease initiation and further development. Nowadays, researchers aim to unravel the exact mechanisms involved in the endogenous ligand-dependent TLR signaling and to discover new potential activators, released during pathological conditions such as atherosclerosis...
Journal Articles
J Innate Immun (2010) 2 (4): 316–324.
Published Online: 17 March 2010
...Nicole A. Braun; Roman Covarrubias; Amy S. Major Atherosclerosis is a chronic inflammatory disease characterized by dyslipidemia and accumulation of lipids in the arterial intima, with activation of both innate and adaptive immunity. Reciprocally, dyslipidemia associated with atherosclerosis can...
Journal Articles
J Innate Immun (2009) 1 (4): 340–349.
Published Online: 08 January 2009
...Clett Erridge Atherosclerosis is a chronic inflammatory disease of the arteries that is characterised by the activation of endothelial cells, the recruitment of monocytes into the vessel wall and the differentiation of recruited macrophages into cholesterol-laden foam cells. Recent evidence from...