...Beatrice Fageräng; Maximilian Peter Götz; Leon Cyranka; Corinna Lau; Per H. Nilsson; Tom Eirik Mollnes; Peter Garred Introduction: We aimed to elucidate the inflammatory response of Aspergillus fumigatus conidia in a whole-blood model of innate immune activation and to compare it with the well...

...Fábio S.Y. Yoshikawa; Maki Wakatsuki; Kosuke Yoshida; Rikio Yabe; Shota Torigoe; Sho Yamasaki; Glen N. Barber; Shinobu Saijo Aspergillus fumigatus is a ubiquitous, yet potentially pathogenic, mold. The immune system employs innate receptors, such as dectin-1, to recognize fungal pathogens...

...Mark S. Gresnigt; Katharina L. Becker; Floris Leenders; M. Fernanda Alonso; Xiaowen Wang; Jacques F. Meis; Judith M. Bain; Lars P. Erwig; Frank L. van de Veerdonk Invasive aspergillosis mainly occurs in immunocompromised patients and is commonly caused by Aspergillus fumigatus , while A.nidulans...

... of neutropenia, the primary risk factor for IA. However, IA is also becoming more appreciated in chronic diseases associated with corticosteroid therapy. The innate immune response to Aspergillus fumigatus , the primary agent in IA, plays a pivotal role in the recognition and elimination of organisms from...