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1-5 of 5
Keywords: Anopheles gambiae
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Journal Articles
Xiufeng Zhang, Shasha Zhang, Junyao Kuang, Kathleen A. Sellens, Bianca Morejon, Sally A. Saab, Miao Li, Eve C. Metto, Chunju An, Christopher T. Culbertson, Mike A. Osta, Caterina Scoglio, Kristin Michel
Journal:
Journal of Innate Immunity
J Innate Immun (2023) 15 (1): 680–696.
Published Online: 13 September 2023
... family members that function in melanization and co-immunoprecipitation using the serine protease inhibitor (SRPN)2, a key negative regulator of the melanization response in mosquitoes, we identify the cSP CLIPB4 from the African malaria mosquito Anopheles gambiae as a central node in this protease...
Journal Articles
Journal:
Journal of Innate Immunity
J Innate Immun (2023) 15 (1): 317–332.
Published Online: 24 November 2022
... Anopheles gambiae . Here, we add yet another dimension to the complex roles underpinning the contributions of cSPHs to mosquito immunity by showing that CLIPA7, a member of the expanded cSPH family, defines a novel branch within the cSPH network that is essential for the melanization of Escherichia coli...
Journal Articles
Journal:
Journal of Innate Immunity
J Innate Immun (2021) 13 (2): 107–126.
Published Online: 18 November 2020
.... Here, we address this question using the pathogenic Serratia marcescens ( Sm ) DB11 strain to establish systemic infections of the malaria vector Anopheles gambiae , either by septic Sm injections or by midgut crossing after feeding on Sm . Using functional genetic studies by RNAi, we report...
Journal Articles
Journal:
Journal of Innate Immunity
J Innate Immun (2016) 8 (3): 314–326.
Published Online: 08 March 2016
...Layla Kamareddine; Johnny Nakhleh; Mike A. Osta The complement-like protein thioester-containing protein 1 (TEP1) is the hallmark effector molecule against Plasmodium ookinetes in the malaria vector Anopheles gambiae . We have previously shown that the knockdown of the noncatalytic clip domain...
Journal Articles
Journal:
Journal of Innate Immunity
J Innate Immun (2014) 6 (6): 806–818.
Published Online: 08 July 2014
... that CLIPA2, a clip domain serine protease homolog of Anopheles gambiae , regulates the consumption of the mosquito complement-like protein TEP1 during systemic bacterial infections. We provide evidence that CLIPA2 localizes to microbial surfaces in a TEP1-dependent manner whereby it negatively regulates...