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Journal Articles

Erratum - IRF1 Is Required for MDA5 (IFIH1) Induction by IFN-α, LPS, and poly(I:C) in Murine Macrophages

Open Access
Subject Area:
Immunology and Allergy
Journal: Journal of Innate Immunity
J Innate Immun (2025) 17 (1): 287.
https://doi.org/10.1159/000545776
Published Online: 11 June 2025
View articletitled, Erratum - IRF1 Is Required for MDA5 (IFIH1) Induction by IFN-α, LPS, and poly(I:C) in Murine Macrophages
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Journal Articles

Emerging advancements in metabolic properties of macrophages within disease microenvironment for immune therapy

Open Access
Subject Area:
Immunology and Allergy
Feng Zhao, Zhongyu Yue, Lijiaqi Zhang, Yujie Qi, Yunting Sun, Shuling Wang, Qingchang Tian
Journal: Journal of Innate Immunity
J Innate Immun (2025)
https://doi.org/10.1159/000546476
Published Online: 11 June 2025
View articletitled, Emerging advancements in metabolic properties of macrophages within disease microenvironment for immune therapy
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Journal Articles

Patients Hospitalized with COVID-19 Demonstrate Distinct Plasma Cytokine and Chemokine Concentrations in vivo and TLR-mediated Cytokine and Chemokine Production in Whole Blood in vitro

Open Access
Subject Area:
Immunology and Allergy
Athena N. Nguyen, Thomas S. Kouyate, Kevin Ryff, Alec L. Plotkin, Simon Doss-Gollin, Sanya Thomas, Kerry McEnaney, Al Ozonoff, Joann Diray-Arce, Ofer Levy, Oludare A. Odumade, Lindsey R. Baden, Simon D. van Haren, Kinga K. Smolen
Journal: Journal of Innate Immunity
J Innate Immun (2025)
https://doi.org/10.1159/000545432
Published Online: 28 May 2025
View articletitled, Patients Hospitalized with COVID-19 Demonstrate Distinct Plasma Cytokine and Chemokine Concentrations in vivo and TLR-mediated Cytokine and Chemokine Production in Whole Blood in vitro
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Journal Articles

TLR2 or TLR4 stimulation induces transmembrane (tm)TNF-driven priming in macrophages which results in improved clearance of a subsequent Staphylococcus aureus infection

Open Access
Subject Area:
Immunology and Allergy
Abby M. Luu, Alexis A. Hatton, Jasper Gattiker, Kelly M. Shepardson, Monica N. Hall, Evelyn Benson, Diane Bimczok, Agnieszka Rynda-Apple
Journal: Journal of Innate Immunity
J Innate Immun (2025)
https://doi.org/10.1159/000546011
Published Online: 28 May 2025
View articletitled, TLR2 or TLR4 stimulation induces transmembrane (tm)TNF-driven priming in macrophages which results in improved clearance of a subsequent Staphylococcus aureus infection
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Journal Articles

Interactions of Probiotics with the Immune Cells of Patients with COVID-19 Pneumonia

Open Access
Subject Area:
Topic Article Package: Coronavirus (COVID-19) , Immunology and Allergy
Ioannis Mitrou, George Dimopoulos, Konstantina Dakou, Panagiotis Koufargyris, Georgia Damoraki, Theologia Gkavogianni, Evangelos J. Giamarellos-Bourboulis
Journal: Journal of Innate Immunity
J Innate Immun (2025) 17 (1): 277–286.
https://doi.org/10.1159/000545873
Published Online: 27 May 2025
View articletitled, Interactions of Probiotics with the Immune Cells of Patients with COVID-19 Pneumonia
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Journal Articles

Qilian Jiechang Ning Alleviates TNBS-Induced Ulcerative Colitis in Mice and Segatella copri Outer Membrane Vesicle-Triggered Inflammation in Colon Epithelial Cells via the Caspase-1/11-GSDMD Pathways

Open Access
Subject Area:
Immunology and Allergy
Jinyang Hu, Junjie Niu, Shisheng Jiang, Yuhua Wu
Journal: Journal of Innate Immunity
J Innate Immun (2025) 17 (1): 262–276.
https://doi.org/10.1159/000545394
Published Online: 14 May 2025
View articletitled, Qilian Jiechang Ning Alleviates TNBS-Induced Ulcerative Colitis in Mice and Segatella copri Outer Membrane Vesicle-Triggered Inflammation in Colon Epithelial Cells via the Caspase-1/11-GSDMD Pathways
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Journal Articles

Development and Characterization of Novel ELISAs for the Specific Quantification of the Factor H-Related Proteins 2, 3, 4, and 5

Open Access
Subject Area:
Immunology and Allergy
Mara van Rossum, Bert R.J. Veuskens, Mieke C. Brouwer, Gerard van Mierlo, Laura Lucientes-Continente, Elena Goicoechea de Jorge, Barbara Uzonyi, Alexandra T. Matola, Mihály Józsi, Günter Müller, Anita M. Meter-Arkema, Felix Poppelaars, Diana Pauly, Richard B. Pouw, Erik J.M. Toonen
Journal: Journal of Innate Immunity
J Innate Immun (2025) 17 (1): 226–243.
https://doi.org/10.1159/000545139
Published Online: 26 March 2025
View articletitled, Development and Characterization of Novel ELISAs for the Specific Quantification of the Factor H-Related Proteins 2, 3, 4, and 5
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Journal Articles

Common Haplotypes within the Chromosome 1q31.3 Region Determine Systemic Concentrations of the Entire Complement Factor H Protein Family

Open Access
Subject Area:
Immunology and Allergy
Bert R.J. Veuskens, Mara van Rossum, Emi Cattenstart, Mieke C. Brouwer, Gerard van Mierlo, Judy Geissler, Karin van Leeuwen, Jin Liu, Robert A. Anstadt, Burt T. Richards, Gregory S. Hageman, Taco W. Kuijpers, Erik J.M. Toonen, Richard B. Pouw
Journal: Journal of Innate Immunity
J Innate Immun (2025) 17 (1): 244–261.
https://doi.org/10.1159/000545342
Published Online: 26 March 2025
View articletitled, Common Haplotypes within the Chromosome 1q31.3 Region Determine Systemic Concentrations of the Entire Complement Factor H Protein Family
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Journal Articles

CAPN1 Promotes Pseudomonas aeruginosa -Induced Infection by Interacting with TFEB and Inhibiting Autophagy

Open Access
Subject Area:
Immunology and Allergy
Yueming Wu, Miaomiao Chen, Hua Chen, Liuhua Pan, Jing Zhao, Shunnan Sun, Ning Zhang, Junlong Xu
Journal: Journal of Innate Immunity
J Innate Immun (2025) 17 (1): 176–197.
https://doi.org/10.1159/000543244
Published Online: 13 March 2025
View articletitled, CAPN1 Promotes Pseudomonas aeruginosa -Induced Infection by Interacting with TFEB and Inhibiting Autophagy
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Journal Articles

Unraveling the Complex Nexus of Macrophage Metabolism, Periodontitis, and Associated Comorbidities

Open Access
Subject Area:
Immunology and Allergy
Zihan Zhang, Yi Liu, Tian Yu, Zhen Liu
Journal: Journal of Innate Immunity
J Innate Immun (2025) 17 (1): 211–225.
https://doi.org/10.1159/000542531
Published Online: 07 March 2025
View articletitled, Unraveling the Complex Nexus of Macrophage Metabolism, Periodontitis, and Associated Comorbidities
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Journal Articles

Streptococcus pyogenes Activates Human Platelets via Streptolysin S-Mediated Calcium Ion Influx

Open Access
Subject Area:
Immunology and Allergy
Anna Riegner, Kristin Jahn, Jan Wesche, Thomas Thiele, Nikolai Siemens
Journal: Journal of Innate Immunity
J Innate Immun (2025) 17 (1): 198–210.
https://doi.org/10.1159/000544951
Published Online: 03 March 2025
View articletitled, Streptococcus pyogenes Activates Human Platelets via Streptolysin S-Mediated Calcium Ion Influx
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Journal Articles

Neutrophils Display Novel Partners of Cytosolic Proliferating Cell Nuclear Antigen Involved in Interferon Response in COVID-19 Patients

Open Access
Subject Area:
Topic Article Package: Coronavirus (COVID-19) , Immunology and Allergy
Lucie Pesenti, Rodrigo de Oliveira Formiga, Nicola Tamassia, Elisa Gardiman, François Chable de La Héronnière, Sara Gasperini, Johana Chicher, Lauriane Kuhn, Philippe Hammann, Morgane Le Gall, Giovanni Saraceni-Tasso, Clémence Martin, Anne Hosmalin, Magali Breckler, Roxane Hervé, Patrice Decker, Maha Zohra Ladjemi, Frédéric Pène, Pierre-Régis Burgel, Marco A. Cassatella, Véronique Witko-Sarsat
Journal: Journal of Innate Immunity
J Innate Immun (2025) 17 (1): 154–175.
https://doi.org/10.1159/000543633
Published Online: 27 February 2025
View articletitled, Neutrophils Display Novel Partners of Cytosolic Proliferating Cell Nuclear Antigen Involved in Interferon Response in COVID-19 Patients
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Journal Articles

Exploring the Role of Macrophages and Their Associated Structures in Rheumatoid Arthritis

Open Access
Subject Area:
Immunology and Allergy
Xin Tian, Jingjing Chen, Yujie Hong, Yang Cao, Jing Xiao, Yan Zhu
Journal: Journal of Innate Immunity
J Innate Immun (2025) 17 (1): 95–111.
https://doi.org/10.1159/000543444
Published Online: 12 February 2025
View articletitled, Exploring the Role of Macrophages and Their Associated Structures in Rheumatoid Arthritis
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Journal Articles

Acinetobacter baumannii Clinical Isolates Resist Complement-Mediated Lysis by Inhibiting the Complement Cascade and Improperly Depositing MAC

Open Access
Subject Area:
Immunology and Allergy
Michal Magda, Wendy Boschloo, Serena Bettoni, Derek Fairley, Thomas A. Russo, Christian G. Giske, Chaitanya Tellapragada, Suzan H.M. Rooijakkers, Kristian Riesbeck, Anna M. Blom
Journal: Journal of Innate Immunity
J Innate Immun (2025) 17 (1): 112–125.
https://doi.org/10.1159/000543664
Published Online: 22 January 2025
View articletitled, Acinetobacter baumannii Clinical Isolates Resist Complement-Mediated Lysis by Inhibiting the Complement Cascade and Improperly Depositing MAC
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Journal Articles

RNA Viruses, Toll-Like Receptors, and Cytokines: The Perfect Storm?

Open Access
Subject Area:
Immunology and Allergy
Sophia K. Stegeman, Olena Kourko, Heather Amsden, Isabella E. Pellizzari Delano, John E. Mamatis, Madison Roth, Che C. Colpitts, Katrina Gee
Journal: Journal of Innate Immunity
J Innate Immun (2025) 17 (1): 126–153.
https://doi.org/10.1159/000543608
Published Online: 16 January 2025
View articletitled, RNA Viruses, Toll-Like Receptors, and Cytokines: The Perfect Storm?
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Journal Articles

5-Methoxytryptophan Protects against Toll-Like Receptor 2-Mediated Renal Tissue Inflammation and Fibrosis in a Murine Unilateral Ureteral Obstruction Model

Open Access
Subject Area:
Immunology and Allergy
Jing-Yiing Wu, Guan-Lin Lee, Yu-Fan Chueh, Cheng-Chin Kuo, Yu-Juei Hsu, Kenneth K. Wu
Journal: Journal of Innate Immunity
J Innate Immun (2025) 17 (1): 78–94.
https://doi.org/10.1159/000543275
Published Online: 07 January 2025
View articletitled, 5-Methoxytryptophan Protects against Toll-Like Receptor 2-Mediated Renal Tissue Inflammation and Fibrosis in a Murine Unilateral Ureteral Obstruction Model
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Journal Articles

Liver X Receptors and Inflammatory-Induced C/EBPβ Selectively Cooperate to Control CD38 Transcription

Open Access
Subject Area:
Immunology and Allergy
Estibaliz Glaría, Pol Rodríguez Martínez, Joan Font-Díaz, Juan Vladimir De la Rosa, Antonio Castrillo, Dylan J. Crawshaw, Jose Manuel Vidal Taboada, Josep Saura, Jonathan Matalonga, Eduardo Nunes Chini, Carme Caelles, Annabel F. Valledor
Journal: Journal of Innate Immunity
J Innate Immun (2025) 17 (1): 56–77.
https://doi.org/10.1159/000543274
Published Online: 19 December 2024
View articletitled, Liver X Receptors and Inflammatory-Induced C/EBPβ Selectively Cooperate to Control CD38 Transcription
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Journal Articles

Acknowledgement to Reviewers

Open Access
Subject Area:
Immunology and Allergy
Journal: Journal of Innate Immunity
J Innate Immun (2024) 16 (1): 595.
https://doi.org/10.1159/000542264
Published Online: 17 December 2024
View articletitled, Acknowledgement to Reviewers
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Journal Articles

Does Adenosine Triphosphate via Purinergic Receptor Signalling Fuel Pulmonary Fibrosis?

Open Access
Subject Area:
Immunology and Allergy
Luke Forde, Debananda Gogoi, Rory Baird, Cormac McCarthy, Michael P. Keane, Emer P. Reeves, Emmet E. McGrath
Journal: Journal of Innate Immunity
J Innate Immun (2025) 17 (1): 44–55.
https://doi.org/10.1159/000543083
Published Online: 11 December 2024
View articletitled, Does Adenosine Triphosphate via Purinergic Receptor Signalling Fuel Pulmonary Fibrosis?
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Journal Articles

Macrophage Evolution during Progression of Hepatitis Virus B-Related Acute-on-Chronic Liver Failure

Open Access
Subject Area:
Immunology and Allergy
Jiawei Rao, Dongmei Ye, Ao Ren, Wenjin He, Xuzhi Zhang, Pengrui Chen, Qian Jian, Zongli Fu, Ronghai Deng, Yixin Hu, Yifang Gao, Yi Ma
Journal: Journal of Innate Immunity
J Innate Immun (2025) 17 (1): 29–43.
https://doi.org/10.1159/000542946
Published Online: 05 December 2024
View articletitled, Macrophage Evolution during Progression of Hepatitis Virus B-Related Acute-on-Chronic Liver Failure
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