Immunology and Allergy

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Research Article

Differential Recognition of Lipopolysaccharide O-Antigens by the Pattern Recognition Molecules MBL and Ficolins of the Complement System

Kirstine Mejlstrup Hymøller; Lisa Crone; Steffen Thiel; Thierry Hennet

https://doi.org/10.1159/000547441

Review Article

Oxidative stress and chronic inflammation as partners in crime in interstitial cystitis/bladder pain syndrome

Aleksandar Janev; Daša Zupančič; Peter Veranič; Tadeja Kuret

https://doi.org/10.1159/000546901

Research Article

TLR9 Downregulation in Breast Cancer: Its Role in Tumor Immunity, Inflammatory Response, and Cellular Senescence

Emily Sible; Gregory Weitsman; Salome Amouyal; Guillaume Roblot; Marie Marotel; Rémi Pescarmona; Nathalie Bendriss-Vermare; Cheryl Gillett; Amie Ceesay; Alexia Gazeu; Marie Cecile Michallet; Christophe Caux; Francois-Loic Cosset; Umaima Al Alem; Tony Ng; Uzma Ayesha Hasan

https://doi.org/10.1159/000545527

Review Article

Interaction between Group 3 Innate Lymphoid Cells, Microbiota, and Intestinal Diseases: Mechanisms and Therapeutic Potential

Lijie Hao; Yi Ge; Zhuo Chen; Duo Yuan; Xiaoyan Zhang; Huihong Zhai; Ziyu Liu

https://doi.org/10.1159/000546972

Erratum

Erratum - IRF1 Is Required for MDA5 (IFIH1) Induction by IFN-α, LPS, and poly(I:C) in Murine Macrophages

https://doi.org/10.1159/000545776

Review Article

Emerging Advancements in Metabolic Properties of Macrophages within Disease Microenvironment for Immune Therapy

Feng Zhao; Zhongyu Yue; Lijiaqi Zhang; Yujie Qi; Yunting Sun; Shuling Wang; Qingchang Tian

https://doi.org/10.1159/000546476

Research Article

Patients Hospitalized with COVID-19 Demonstrate Distinct Plasma Cytokine and Chemokine Concentrations in vivo and TLR-Mediated Cytokine and Chemokine Production in Whole Blood in vitro

Athena N. Nguyen; Thomas S. Kouyate; Kevin Ryff; Alec L. Plotkin; Simon Doss-Gollin; Sanya Thomas; Kerry McEnaney; Al Ozonoff; Joann Diray-Arce; Ofer Levy; Oludare A. Odumade; Lindsey R. Baden; Simon D. van Haren; Kinga K. Smolen; On behalf of the IMPACC - Boston Team

https://doi.org/10.1159/000545432

Editor's choice Research Article

TLR2 or TLR4 Stimulation Induces Transmembrane TNF-Driven Priming in Macrophages Which Results in Improved Clearance of a Subsequent Staphylococcus aureus Infection

Abby M. Luu; Alexis A. Hatton; Jasper Gattiker; Kelly M. Shepardson; Monica N. Hall; Evelyn Benson; Diane Bimczok; Agnieszka Rynda-Apple

https://doi.org/10.1159/000546011

Research Article

Interactions of Probiotics with the Immune Cells of Patients with COVID-19 Pneumonia

Ioannis Mitrou; George Dimopoulos; Konstantina Dakou; Panagiotis Koufargyris; Georgia Damoraki; Theologia Gkavogianni; Evangelos J. Giamarellos-Bourboulis

https://doi.org/10.1159/000545873

Research Article

Qilian Jiechang Ning Alleviates TNBS-Induced Ulcerative Colitis in Mice and Segatella copri Outer Membrane Vesicle-Triggered Inflammation in Colon Epithelial Cells via the Caspase-1/11-GSDMD Pathways

Jinyang Hu; Junjie Niu; Shisheng Jiang; Yuhua Wu

https://doi.org/10.1159/000545394

Research Article

Development and Characterization of Novel ELISAs for the Specific Quantification of the Factor H-Related Proteins 2, 3, 4, and 5

Mara van Rossum; Bert R.J. Veuskens; Mieke C. Brouwer; Gerard van Mierlo; Laura Lucientes-Continente; Elena Goicoechea de Jorge; Barbara Uzonyi; Alexandra T. Matola; Mihály Józsi; Günter Müller; Anita M. Meter-Arkema; Felix Poppelaars; Diana Pauly; Richard B. Pouw; Erik J.M. Toonen

https://doi.org/10.1159/000545139

Research Article

Common Haplotypes within the Chromosome 1q31.3 Region Determine Systemic Concentrations of the Entire Complement Factor H Protein Family

Bert R.J. Veuskens; Mara van Rossum; Emi Cattenstart; Mieke C. Brouwer; Gerard van Mierlo; Judy Geissler; Karin van Leeuwen; Jin Liu; Robert A. Anstadt; Burt T. Richards; Gregory S. Hageman; Taco W. Kuijpers; Erik J.M. Toonen; Richard B. Pouw

https://doi.org/10.1159/000545342

Research Article

CAPN1 Promotes Pseudomonas aeruginosa -Induced Infection by Interacting with TFEB and Inhibiting Autophagy

Yueming Wu; Miaomiao Chen; Hua Chen; Liuhua Pan; Jing Zhao; Shunnan Sun; Ning Zhang; Junlong Xu

https://doi.org/10.1159/000543244

Review Article

Unraveling the Complex Nexus of Macrophage Metabolism, Periodontitis, and Associated Comorbidities

Zihan Zhang; Yi Liu; Tian Yu; Zhen Liu

https://doi.org/10.1159/000542531

Research Article

Streptococcus pyogenes Activates Human Platelets via Streptolysin S-Mediated Calcium Ion Influx

Anna Riegner; Kristin Jahn; Jan Wesche; Thomas Thiele; Nikolai Siemens

https://doi.org/10.1159/000544951

Editor's choice Research Article

Neutrophils Display Novel Partners of Cytosolic Proliferating Cell Nuclear Antigen Involved in Interferon Response in COVID-19 Patients

Lucie Pesenti; Rodrigo de Oliveira Formiga; Nicola Tamassia; Elisa Gardiman; François Chable de La Héronnière; Sara Gasperini; Johana Chicher; Lauriane Kuhn; Philippe Hammann; Morgane Le Gall; Giovanni Saraceni-Tasso; Clémence Martin; Anne Hosmalin; Magali Breckler; Roxane Hervé; Patrice Decker; Maha Zohra Ladjemi; Frédéric Pène; Pierre-Régis Burgel; Marco A. Cassatella; Véronique Witko-Sarsat

https://doi.org/10.1159/000543633

Review Article

Exploring the Role of Macrophages and Their Associated Structures in Rheumatoid Arthritis

Xin Tian; Jingjing Chen; Yujie Hong; Yang Cao; Jing Xiao; Yan Zhu

https://doi.org/10.1159/000543444

Research Article

Acinetobacter baumannii Clinical Isolates Resist Complement-Mediated Lysis by Inhibiting the Complement Cascade and Improperly Depositing MAC

Michal Magda; Wendy Boschloo; Serena Bettoni; Derek Fairley; Thomas A. Russo; Christian G. Giske; Chaitanya Tellapragada; Suzan H.M. Rooijakkers; Kristian Riesbeck; Anna M. Blom

https://doi.org/10.1159/000543664

Review Article

RNA Viruses, Toll-Like Receptors, and Cytokines: The Perfect Storm?

Sophia K. Stegeman; Olena Kourko; Heather Amsden; Isabella E. Pellizzari Delano; John E. Mamatis; Madison Roth; Che C. Colpitts; Katrina Gee

https://doi.org/10.1159/000543608

Editor's choice Research Article

5-Methoxytryptophan Protects against Toll-Like Receptor 2-Mediated Renal Tissue Inflammation and Fibrosis in a Murine Unilateral Ureteral Obstruction Model

Jing-Yiing Wu; Guan-Lin Lee; Yu-Fan Chueh; Cheng-Chin Kuo; Yu-Juei Hsu; Kenneth K. Wu

https://doi.org/10.1159/000543275